Impact of a prenatal screening program on the Down syndrome phenotype: An interrupted time series analysis
Abstract Introduction We hypothesized that children with Down syndrome who were born after the implementation of first‐trimester combined screening for trisomy 13, 18, and 21 and a second‐trimester ultrasound scan in Denmark would show a milder syndrome phenotype. We investigated the birth biometry,...
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| Main Authors: | Ellen Hollands Steffensen, Lars Henning Pedersen, Stina Lou, Ida Vogel, The Danish Cytogenetic Central Registry Study Group |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-06-01
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| Series: | Acta Obstetricia et Gynecologica Scandinavica |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/aogs.14573 |
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