Association rules analysis on patterns of multimorbidity in adults: based on the National Health and Nutrition Examination Surveys database
Objective To explore the prevalence and patterns of multimorbidity in population with different genders and age ranges.Design A cross-sectional study.Setting National Health and Nutrition Examination Surveys database.Participants 12 576 patients.Primary and secondary outcome measures The prevalence...
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BMJ Publishing Group
2022-12-01
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| Series: | BMJ Open |
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| author | Lin Chen Yangli Xie Zheng Zheng Junlan Huang Xianding Sun Ruobin Zhang |
| author_facet | Lin Chen Yangli Xie Zheng Zheng Junlan Huang Xianding Sun Ruobin Zhang |
| author_sort | Lin Chen |
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| description | Objective To explore the prevalence and patterns of multimorbidity in population with different genders and age ranges.Design A cross-sectional study.Setting National Health and Nutrition Examination Surveys database.Participants 12 576 patients.Primary and secondary outcome measures The prevalence and patterns of multimorbidity.Results High cholesterol had the highest prevalence in all population (33.4 (95% CI: 32.0 to 34.9)) and males. In females <65 years, the most prevalent disease was sleep disorder (32.1 (95% CI: 29.6 to 34.5)) while in females ≥65 years, hypertension was the most prevalent disease (63.9 (95% CI: 59.9 to 67.9)). Hypertension and high cholesterol were associated with the highest support (occur together most frequently) in all population regardless of genders. Hypertension displayed the highest betweenness centrality (mediating role in the network) followed by high cholesterol and arthritis in all population. For males aged <65 years, hypertension and high cholesterol presented the highest betweenness centrality. In males ≥65 years, hypertension, high cholesterol and arthritis were the top three diseases of degree centrality (direct association with other conditions). As for females ≥65 years, hypertension showed the highest betweenness centrality followed by high cholesterol and arthritis. The associations of hypertension, arthritis and one other item with high cholesterol presented the highest support in all population. In males, the associations of depression, hypertension with sleep disorders had the highest lift (the chance of co-occurrence of the conditions and significant association). Among females, the associations of depression, arthritis with sleep disorders had the highest lift.Conclusion Hypertension and high cholesterol were prevalent in all population, regardless of females and males. Hypertension and high cholesterol, arthritis and hypertension, and diabetes and hypertension were more likely to coexist. The findings of this study might help make plans for the management and primary care of people with one or more diseases. |
| format | Article |
| id | doaj-art-3d0620bc7642475bb34f588eed44317e |
| institution | DOAJ |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-3d0620bc7642475bb34f588eed44317e2025-08-20T02:57:22ZengBMJ Publishing GroupBMJ Open2044-60552022-12-01121210.1136/bmjopen-2022-063660Association rules analysis on patterns of multimorbidity in adults: based on the National Health and Nutrition Examination Surveys databaseLin Chen0Yangli Xie1Zheng Zheng2Junlan Huang3Xianding Sun4Ruobin Zhang5Department of Gastrointestinal Surgery, Peking University International Hospital, Beijing, ChinaDepartment Of Wound Repair and Rehabilitation Medicine, Center of Bone Metabolism and Repair, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Daping Hospital, Army Medical University, Chongqing, ChinaDepartment Of Wound Repair and Rehabilitation Medicine, Center of Bone Metabolism and Repair, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Daping Hospital, Army Medical University, Chongqing, ChinaDepartment Of Wound Repair and Rehabilitation Medicine, Center of Bone Metabolism and Repair, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Daping Hospital, Army Medical University, Chongqing, ChinaDepartment of Orthopaedics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, ChinaDepartment Of Wound Repair and Rehabilitation Medicine, Center of Bone Metabolism and Repair, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Daping Hospital, Army Medical University, Chongqing, ChinaObjective To explore the prevalence and patterns of multimorbidity in population with different genders and age ranges.Design A cross-sectional study.Setting National Health and Nutrition Examination Surveys database.Participants 12 576 patients.Primary and secondary outcome measures The prevalence and patterns of multimorbidity.Results High cholesterol had the highest prevalence in all population (33.4 (95% CI: 32.0 to 34.9)) and males. In females <65 years, the most prevalent disease was sleep disorder (32.1 (95% CI: 29.6 to 34.5)) while in females ≥65 years, hypertension was the most prevalent disease (63.9 (95% CI: 59.9 to 67.9)). Hypertension and high cholesterol were associated with the highest support (occur together most frequently) in all population regardless of genders. Hypertension displayed the highest betweenness centrality (mediating role in the network) followed by high cholesterol and arthritis in all population. For males aged <65 years, hypertension and high cholesterol presented the highest betweenness centrality. In males ≥65 years, hypertension, high cholesterol and arthritis were the top three diseases of degree centrality (direct association with other conditions). As for females ≥65 years, hypertension showed the highest betweenness centrality followed by high cholesterol and arthritis. The associations of hypertension, arthritis and one other item with high cholesterol presented the highest support in all population. In males, the associations of depression, hypertension with sleep disorders had the highest lift (the chance of co-occurrence of the conditions and significant association). Among females, the associations of depression, arthritis with sleep disorders had the highest lift.Conclusion Hypertension and high cholesterol were prevalent in all population, regardless of females and males. Hypertension and high cholesterol, arthritis and hypertension, and diabetes and hypertension were more likely to coexist. The findings of this study might help make plans for the management and primary care of people with one or more diseases.https://bmjopen.bmj.com/content/12/12/e063660.full |
| spellingShingle | Lin Chen Yangli Xie Zheng Zheng Junlan Huang Xianding Sun Ruobin Zhang Association rules analysis on patterns of multimorbidity in adults: based on the National Health and Nutrition Examination Surveys database BMJ Open |
| title | Association rules analysis on patterns of multimorbidity in adults: based on the National Health and Nutrition Examination Surveys database |
| title_full | Association rules analysis on patterns of multimorbidity in adults: based on the National Health and Nutrition Examination Surveys database |
| title_fullStr | Association rules analysis on patterns of multimorbidity in adults: based on the National Health and Nutrition Examination Surveys database |
| title_full_unstemmed | Association rules analysis on patterns of multimorbidity in adults: based on the National Health and Nutrition Examination Surveys database |
| title_short | Association rules analysis on patterns of multimorbidity in adults: based on the National Health and Nutrition Examination Surveys database |
| title_sort | association rules analysis on patterns of multimorbidity in adults based on the national health and nutrition examination surveys database |
| url | https://bmjopen.bmj.com/content/12/12/e063660.full |
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