Ubiquitin-specific peptidases in lymphoma: a path to novel therapeutics

Ubiquitin-specific peptidases in lymphoma: a path to novel therapeutics

BackgroundUbiquitin-specific peptidases (USPs), also known as deubiquitinating enzymes (DUBs), play a crucial role in maintaining cellular homeostasis by selectively removing ubiquitin molecules from targeted proteins. This process affects protein stability, subcellular localization, and activity, t...

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Main Authors: Maryam Samareh Salavatipour, Shirin Tavakoli, Aram Halimi, Shima Tavoosi, Amir-Hossein Baghsheikhi, Abdolkarim Talebi-Taheri, Mehdi Niloufari, Zahra Salehi, Javad Verdi, Soheila Rahgozar, Alireza Mosavi-Jarrahi, Mohammad Ahmadvand
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
Subjects:
ubiquitin-specific peptidases
USPs
cancer
lymphoma
non-Hodgkin
Hodgkin
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1356634/full
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