Comparative immunogenicity of monovalent and bivalent adenovirus vaccines carrying spikes of early and late SARS-CoV-2 variants

Comparative immunogenicity of monovalent and bivalent adenovirus vaccines carrying spikes of early and late SARS-CoV-2 variants

The continuous emergence of highly immune-evasive SARS-CoV-2 variants has challenged vaccine efficacy. A vaccine that can provide broad protection is desirable. We evaluated the immunogenicity of a series of monovalent and bivalent adenovirus-vectored vaccines containing the spikes of Wildtype (WT),...

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Bibliographic Details
Main Authors: Hengchun Li, Chenchen Yang, Li Yin, Wenming Liu, Zhengyuan Zhang, Bo Liu, Xinxin Sun, Wenhao Liu, Zihan Lin, Zijian Liu, Ping He, Ying Feng, Chunhua Wang, Wei Wang, Suhua Guan, Qian Wang, Ling Chen, Pingchao Li
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
Adenovirus
COVID-19
Omicron
monovalent vaccine
bivalent vaccine
immunogenicity
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2387447
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