Death by Frostbite: From Theory to Reality: A Case Report

<b>Background:</b> When the body temperature falls below 35 °C, a condition known as hypothermia occurs. This renders it impossible to regulate the body temperature and produce heat. In these cases, death is due to a cessation of vital functions and is triggered by a body temperature bel...

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Main Authors: Stefano Duma, Federica Mele, Mariagrazia Calvano, Mirko Leonardelli, Enrica Macorano, Giovanni De Gabriele, Alessandro Cristalli, Andrea Marzullo, Francesco Introna
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Forensic Sciences
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Online Access:https://www.mdpi.com/2673-6756/4/4/37
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author Stefano Duma
Federica Mele
Mariagrazia Calvano
Mirko Leonardelli
Enrica Macorano
Giovanni De Gabriele
Alessandro Cristalli
Andrea Marzullo
Francesco Introna
author_facet Stefano Duma
Federica Mele
Mariagrazia Calvano
Mirko Leonardelli
Enrica Macorano
Giovanni De Gabriele
Alessandro Cristalli
Andrea Marzullo
Francesco Introna
author_sort Stefano Duma
collection DOAJ
description <b>Background:</b> When the body temperature falls below 35 °C, a condition known as hypothermia occurs. This renders it impossible to regulate the body temperature and produce heat. In these cases, death is due to a cessation of vital functions and is triggered by a body temperature below 25 °C. A multidisciplinary approach is typically required when hypothermia is suspected to combine circumstantial evidence, external examination, autopsy, microscopic and biochemical findings, and other data useful to assess the diagnosis of fatal hypothermia. Post-mortem diagnosis of death by hypothermia frequently presents a medico-legal dilemma. <b>Methods and Results:</b> The authors present a case of hypothermia in which site inspection, autopsy, and histological examination simultaneously revealed the forensic and anatomopathological characteristic findings of hypothermia with some peculiar evidence: paradoxical undressing, thanatochronological phenomena, frost erythema, polyvisceral congestion and Wischnewski spots, and subnuclear vacuolization of renal tubular epithelial cells.
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institution Kabale University
issn 2673-6756
language English
publishDate 2024-10-01
publisher MDPI AG
record_format Article
series Forensic Sciences
spelling doaj-art-3cf85855fef04a099b5e51d9bb78f9bd2024-12-27T14:26:52ZengMDPI AGForensic Sciences2673-67562024-10-014455556510.3390/forensicsci4040037Death by Frostbite: From Theory to Reality: A Case ReportStefano Duma0Federica Mele1Mariagrazia Calvano2Mirko Leonardelli3Enrica Macorano4Giovanni De Gabriele5Alessandro Cristalli6Andrea Marzullo7Francesco Introna8Department of Interdisciplinary Medicine, Section of Legal Medicine, Aldo Moro University of Bari, Piazza Giulio Cesare, 11, 70124 Bari, ItalyDepartment of Interdisciplinary Medicine, Section of Legal Medicine, Aldo Moro University of Bari, Piazza Giulio Cesare, 11, 70124 Bari, ItalyDepartment of Interdisciplinary Medicine, Section of Legal Medicine, Aldo Moro University of Bari, Piazza Giulio Cesare, 11, 70124 Bari, ItalyDepartment of Interdisciplinary Medicine, Section of Legal Medicine, Aldo Moro University of Bari, Piazza Giulio Cesare, 11, 70124 Bari, ItalyDepartment of Interdisciplinary Medicine, Section of Legal Medicine, Aldo Moro University of Bari, Piazza Giulio Cesare, 11, 70124 Bari, ItalyDepartment of Interdisciplinary Medicine, Section of Legal Medicine, Aldo Moro University of Bari, Piazza Giulio Cesare, 11, 70124 Bari, ItalyDepartment of Interdisciplinary Medicine, Section of Legal Medicine, Aldo Moro University of Bari, Piazza Giulio Cesare, 11, 70124 Bari, ItalyDepartment of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), Section of Pathology, Aldo Moro University of Bari, 70124 Bari, ItalyDepartment of Interdisciplinary Medicine, Section of Legal Medicine, Aldo Moro University of Bari, Piazza Giulio Cesare, 11, 70124 Bari, Italy<b>Background:</b> When the body temperature falls below 35 °C, a condition known as hypothermia occurs. This renders it impossible to regulate the body temperature and produce heat. In these cases, death is due to a cessation of vital functions and is triggered by a body temperature below 25 °C. A multidisciplinary approach is typically required when hypothermia is suspected to combine circumstantial evidence, external examination, autopsy, microscopic and biochemical findings, and other data useful to assess the diagnosis of fatal hypothermia. Post-mortem diagnosis of death by hypothermia frequently presents a medico-legal dilemma. <b>Methods and Results:</b> The authors present a case of hypothermia in which site inspection, autopsy, and histological examination simultaneously revealed the forensic and anatomopathological characteristic findings of hypothermia with some peculiar evidence: paradoxical undressing, thanatochronological phenomena, frost erythema, polyvisceral congestion and Wischnewski spots, and subnuclear vacuolization of renal tubular epithelial cells.https://www.mdpi.com/2673-6756/4/4/37frostbite deathparadoxical undressingfrost erythemaWischnewski spotrenal tubular vacuolization
spellingShingle Stefano Duma
Federica Mele
Mariagrazia Calvano
Mirko Leonardelli
Enrica Macorano
Giovanni De Gabriele
Alessandro Cristalli
Andrea Marzullo
Francesco Introna
Death by Frostbite: From Theory to Reality: A Case Report
Forensic Sciences
frostbite death
paradoxical undressing
frost erythema
Wischnewski spot
renal tubular vacuolization
title Death by Frostbite: From Theory to Reality: A Case Report
title_full Death by Frostbite: From Theory to Reality: A Case Report
title_fullStr Death by Frostbite: From Theory to Reality: A Case Report
title_full_unstemmed Death by Frostbite: From Theory to Reality: A Case Report
title_short Death by Frostbite: From Theory to Reality: A Case Report
title_sort death by frostbite from theory to reality a case report
topic frostbite death
paradoxical undressing
frost erythema
Wischnewski spot
renal tubular vacuolization
url https://www.mdpi.com/2673-6756/4/4/37
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