Integrated analysis of serum metabolomics and fecal microbiome in infants with necrotizing enterocolitis

Integrated analysis of serum metabolomics and fecal microbiome in infants with necrotizing enterocolitis

BackgroundNecrotizing enterocolitis (NEC), a lethal gastrointestinal disorder in preterm infants, remains poorly understood in its pathology, and early diagnosis are critically limited. Multi-omics approaches present unprecedented opportunities to elucidate NEC pathogenesis and identify clinically t...

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Main Authors: Zhi-ying Lin, Shan-shan He, Zi-tong Mo, Xiao-tian Liao, Zhou-shan Feng, Juan Kong, Lu Zhu, Ying Li, Hui-yuan Tan, Zhi-wen Su, Chun-hong Jia, Fan Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Microbiology
Subjects:
preterm infant
necrotizing enterocolitis
microbiome
metabolomics
multi-omics
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1584041/full
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