Effects of Monosodium Glutamate Oral Administration on LH and Testosterone Levels in Serum of Adult Male Rats (Rattus norvegicus)
This study aims to determine the effect of monosodium glutamate on LH and testosterone levels in serum of adult male rats (Rattus norvegicus). A total of 12 male Wistar-strained rats divided into three groups with 4 rats per group. Control group was given distilled water, while M1 was given MSG at a...
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| Format: | Article |
| Language: | English |
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University of Brawijaya
2019-06-01
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| Series: | Journal of Experimental Life Science |
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| Online Access: | https://jels.ub.ac.id/index.php/jels/article/view/341 |
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| author | Riska Annisa Moch. Sasmito Djati Sri Rahayu |
| author_facet | Riska Annisa Moch. Sasmito Djati Sri Rahayu |
| author_sort | Riska Annisa |
| collection | DOAJ |
| description | This study aims to determine the effect of monosodium glutamate on LH and testosterone levels in serum of adult male rats (Rattus norvegicus). A total of 12 male Wistar-strained rats divided into three groups with 4 rats per group. Control group was given distilled water, while M1 was given MSG at a dose of 4mg g-1 BW for 15 days and M2 was given MSG at a dose of 4 mg g-1BW for 45 days. All substances were given orally. At the end of the study, rats were sacrificed with a dislocation to draw blood from the heart. Then, the blood was incubated at room temperature to obtain serum. Serum was used to analyze LH and testosterone levels using the ELISA kit. Data were analyzed using one way ANOVA (p ≤ 0.05) with SPPS 16.0 for windows. The results showed that serum LH levels after MSG treatments for 45 days was significantly decreased compared with the control. The serum testosterone levels M2 was significantly difference with the control group (p ≤ 0.01). This study predicts that monosodium glutamate have a direct and indirect effect on male reproductive organs. |
| format | Article |
| id | doaj-art-3ce3afe1e169479a904b0aae9052e8ff |
| institution | Kabale University |
| issn | 2087-2852 2338-1655 |
| language | English |
| publishDate | 2019-06-01 |
| publisher | University of Brawijaya |
| record_format | Article |
| series | Journal of Experimental Life Science |
| spelling | doaj-art-3ce3afe1e169479a904b0aae9052e8ff2025-08-20T03:49:41ZengUniversity of BrawijayaJournal of Experimental Life Science2087-28522338-16552019-06-0192105109https://doi.org/10.21776/ub.jels.2019.009.02.07Effects of Monosodium Glutamate Oral Administration on LH and Testosterone Levels in Serum of Adult Male Rats (Rattus norvegicus)Riska Annisa0Moch. Sasmito Djati1Sri Rahayu2Universitas BrawijayaUniversitas BrawijayaUniversitas BrawijayaThis study aims to determine the effect of monosodium glutamate on LH and testosterone levels in serum of adult male rats (Rattus norvegicus). A total of 12 male Wistar-strained rats divided into three groups with 4 rats per group. Control group was given distilled water, while M1 was given MSG at a dose of 4mg g-1 BW for 15 days and M2 was given MSG at a dose of 4 mg g-1BW for 45 days. All substances were given orally. At the end of the study, rats were sacrificed with a dislocation to draw blood from the heart. Then, the blood was incubated at room temperature to obtain serum. Serum was used to analyze LH and testosterone levels using the ELISA kit. Data were analyzed using one way ANOVA (p ≤ 0.05) with SPPS 16.0 for windows. The results showed that serum LH levels after MSG treatments for 45 days was significantly decreased compared with the control. The serum testosterone levels M2 was significantly difference with the control group (p ≤ 0.01). This study predicts that monosodium glutamate have a direct and indirect effect on male reproductive organs.https://jels.ub.ac.id/index.php/jels/article/view/341luteinizing hormonemonosodium glutamatetestosterone |
| spellingShingle | Riska Annisa Moch. Sasmito Djati Sri Rahayu Effects of Monosodium Glutamate Oral Administration on LH and Testosterone Levels in Serum of Adult Male Rats (Rattus norvegicus) Journal of Experimental Life Science luteinizing hormone monosodium glutamate testosterone |
| title | Effects of Monosodium Glutamate Oral Administration on LH and Testosterone Levels in Serum of Adult Male Rats (Rattus norvegicus) |
| title_full | Effects of Monosodium Glutamate Oral Administration on LH and Testosterone Levels in Serum of Adult Male Rats (Rattus norvegicus) |
| title_fullStr | Effects of Monosodium Glutamate Oral Administration on LH and Testosterone Levels in Serum of Adult Male Rats (Rattus norvegicus) |
| title_full_unstemmed | Effects of Monosodium Glutamate Oral Administration on LH and Testosterone Levels in Serum of Adult Male Rats (Rattus norvegicus) |
| title_short | Effects of Monosodium Glutamate Oral Administration on LH and Testosterone Levels in Serum of Adult Male Rats (Rattus norvegicus) |
| title_sort | effects of monosodium glutamate oral administration on lh and testosterone levels in serum of adult male rats rattus norvegicus |
| topic | luteinizing hormone monosodium glutamate testosterone |
| url | https://jels.ub.ac.id/index.php/jels/article/view/341 |
| work_keys_str_mv | AT riskaannisa effectsofmonosodiumglutamateoraladministrationonlhandtestosteronelevelsinserumofadultmaleratsrattusnorvegicus AT mochsasmitodjati effectsofmonosodiumglutamateoraladministrationonlhandtestosteronelevelsinserumofadultmaleratsrattusnorvegicus AT srirahayu effectsofmonosodiumglutamateoraladministrationonlhandtestosteronelevelsinserumofadultmaleratsrattusnorvegicus |