Machine learning for diabetic foot care: accuracy trends and emerging directions in healthcare AI

BackgroundDiabetic foot is a common and debilitating complication of diabetes that significantly impacts patients’ quality of life and frequently leads to amputation. In parallel, artificial intelligence (AI), particularly machine learning (ML), has emerged as a powerful tool in healthcare, offering...

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Main Authors: Pei-Chun Lin, Tsai-Chung Li, Tzu-Hsuan Huang, Ying-Lin Hsu, Wen-Chao Ho, Jia-Lang Xu, Ching-Liang Hsieh, Zih-En Jhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Public Health
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Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2025.1613946/full
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author Pei-Chun Lin
Pei-Chun Lin
Tsai-Chung Li
Tsai-Chung Li
Tzu-Hsuan Huang
Ying-Lin Hsu
Wen-Chao Ho
Jia-Lang Xu
Ching-Liang Hsieh
Ching-Liang Hsieh
Ching-Liang Hsieh
Zih-En Jhang
author_facet Pei-Chun Lin
Pei-Chun Lin
Tsai-Chung Li
Tsai-Chung Li
Tzu-Hsuan Huang
Ying-Lin Hsu
Wen-Chao Ho
Jia-Lang Xu
Ching-Liang Hsieh
Ching-Liang Hsieh
Ching-Liang Hsieh
Zih-En Jhang
author_sort Pei-Chun Lin
collection DOAJ
description BackgroundDiabetic foot is a common and debilitating complication of diabetes that significantly impacts patients’ quality of life and frequently leads to amputation. In parallel, artificial intelligence (AI), particularly machine learning (ML), has emerged as a powerful tool in healthcare, offering novel solutions for disease prediction, monitoring, and management. Despite growing interest, a systematic overview of machine learning applications in diabetic foot research is still lacking.ObjectiveThis study aims to systematically analyze recent literature to identify key trends, focus areas, and methodological approaches in the application of machine learning to diabetic foot research.Data sourcesA comprehensive literature search was conducted across three major databases: Web of Science (WoS), IEEE Xplore, and PubMed. The search targeted peer-reviewed journal articles published between 2020 and 2024 that focused on the intersection of machine learning and diabetic foot management.Eligibility criteria and study selectionArticles were included if they were indexed in the Science Citation Index (SCI) or Social Sciences Citation Index (SSCI), published in English. They explored the use of machine learning in diabetic foot-related applications. After removing duplicates and irrelevant entries, 25 original research articles were included for review.ResultsThere has been a steady increase in publications related to machine learning in diabetic foot research over the past 5 years. Among the 25 studies included, image analysis was the most prevalent theme (12 articles), dominated by thermal imaging applications (10 articles). General clinical imaging was less common (2 articles). Seven studies focused on structured clinical data analysis, while six explored IoT-based approaches such as smart insoles with integrated sensors for real-time foot monitoring. Citation analysis showed that Computers in Biology and Medicine and Sensors had the highest average citation rates among journals publishing multiple relevant studies.ConclusionThe integration of machine learning into diabetic foot research is rapidly evolving; it is characterized by growing diversity in data modalities and analytical techniques. Thermal imaging remains a key area of interest, while IoT innovations show promise for clinical translation. Future studies should aim to incorporate deep learning, genomic data, and large language models to further enhance the scope and clinical utility of diabetic foot research.
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spelling doaj-art-3ce12d899ff84de7a7990c827559a0142025-08-20T03:51:09ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-07-011310.3389/fpubh.2025.16139461613946Machine learning for diabetic foot care: accuracy trends and emerging directions in healthcare AIPei-Chun Lin0Pei-Chun Lin1Tsai-Chung Li2Tsai-Chung Li3Tzu-Hsuan Huang4Ying-Lin Hsu5Wen-Chao Ho6Jia-Lang Xu7Ching-Liang Hsieh8Ching-Liang Hsieh9Ching-Liang Hsieh10Zih-En Jhang11Department of Public Health, College of Public Health, China Medical University, Taichung, TaiwanInstitute of Population Health Sciences, National Health Research Institutes, Miaoli, TaiwanDepartment of Public Health, College of Public Health, China Medical University, Taichung, TaiwanDepartment of Audiology and Speech-Language Pathology, College of Medical and Health Sciences, Asia University, Taichung, TaiwanDoctoral Program in Big Data Analytics for Industrial Applications, Nation Chung Hsing University, Taichung, TaiwanDepartment of Applied Mathematics and Institute of Statistics, National Chung Hsing University, Taichung, TaiwanDepartment of Public Health, College of Public Health, China Medical University, Taichung, TaiwanDepartment of Computer Science and Information Engineering, Chaoyang University of Technology, Taichung, TaiwanDepartment of Chinese Medicine, China Medical University Hospital, Taichung, TaiwanGraduate Institute of Acupuncture Science, College of Chinese Medicine, China Medical University, Taichung, TaiwanChinese Medicine Research Center, China Medical University, Taichung, Taiwan0Department of Medical Imaging, Changhua Christian Hospital, Changhua, TaiwanBackgroundDiabetic foot is a common and debilitating complication of diabetes that significantly impacts patients’ quality of life and frequently leads to amputation. In parallel, artificial intelligence (AI), particularly machine learning (ML), has emerged as a powerful tool in healthcare, offering novel solutions for disease prediction, monitoring, and management. Despite growing interest, a systematic overview of machine learning applications in diabetic foot research is still lacking.ObjectiveThis study aims to systematically analyze recent literature to identify key trends, focus areas, and methodological approaches in the application of machine learning to diabetic foot research.Data sourcesA comprehensive literature search was conducted across three major databases: Web of Science (WoS), IEEE Xplore, and PubMed. The search targeted peer-reviewed journal articles published between 2020 and 2024 that focused on the intersection of machine learning and diabetic foot management.Eligibility criteria and study selectionArticles were included if they were indexed in the Science Citation Index (SCI) or Social Sciences Citation Index (SSCI), published in English. They explored the use of machine learning in diabetic foot-related applications. After removing duplicates and irrelevant entries, 25 original research articles were included for review.ResultsThere has been a steady increase in publications related to machine learning in diabetic foot research over the past 5 years. Among the 25 studies included, image analysis was the most prevalent theme (12 articles), dominated by thermal imaging applications (10 articles). General clinical imaging was less common (2 articles). Seven studies focused on structured clinical data analysis, while six explored IoT-based approaches such as smart insoles with integrated sensors for real-time foot monitoring. Citation analysis showed that Computers in Biology and Medicine and Sensors had the highest average citation rates among journals publishing multiple relevant studies.ConclusionThe integration of machine learning into diabetic foot research is rapidly evolving; it is characterized by growing diversity in data modalities and analytical techniques. Thermal imaging remains a key area of interest, while IoT innovations show promise for clinical translation. Future studies should aim to incorporate deep learning, genomic data, and large language models to further enhance the scope and clinical utility of diabetic foot research.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1613946/fulldiabetic footmachine learningthermal imagingclinical data analysisinternet of thingsartificial intelligence in healthcare
spellingShingle Pei-Chun Lin
Pei-Chun Lin
Tsai-Chung Li
Tsai-Chung Li
Tzu-Hsuan Huang
Ying-Lin Hsu
Wen-Chao Ho
Jia-Lang Xu
Ching-Liang Hsieh
Ching-Liang Hsieh
Ching-Liang Hsieh
Zih-En Jhang
Machine learning for diabetic foot care: accuracy trends and emerging directions in healthcare AI
Frontiers in Public Health
diabetic foot
machine learning
thermal imaging
clinical data analysis
internet of things
artificial intelligence in healthcare
title Machine learning for diabetic foot care: accuracy trends and emerging directions in healthcare AI
title_full Machine learning for diabetic foot care: accuracy trends and emerging directions in healthcare AI
title_fullStr Machine learning for diabetic foot care: accuracy trends and emerging directions in healthcare AI
title_full_unstemmed Machine learning for diabetic foot care: accuracy trends and emerging directions in healthcare AI
title_short Machine learning for diabetic foot care: accuracy trends and emerging directions in healthcare AI
title_sort machine learning for diabetic foot care accuracy trends and emerging directions in healthcare ai
topic diabetic foot
machine learning
thermal imaging
clinical data analysis
internet of things
artificial intelligence in healthcare
url https://www.frontiersin.org/articles/10.3389/fpubh.2025.1613946/full
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