Endurance training promotes chromatin closure and timely repression of the post-exercise immediate early stress response

Endurance training promotes chromatin closure and timely repression of the post-exercise immediate early stress response

Objectives: Endurance training is known to elicit numerous changes in skeletal muscle to enhance performance and function. Many of these adaptations are controlled by the modulation of transcriptional programs in myonuclei. While previous studies have explored alterations in DNA methylation and hist...

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Bibliographic Details
Main Authors: Laura M. de Smalen, Volkan Adak, Aurel B. Leuchtmann, Konstantin Schneider-Heieck, Stefan A. Steurer, Christoph Handschin
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Molecular Metabolism
Subjects:
Exercise
Endurance training
Skeletal muscle plasticity
Chromatin accessibility
Immediate early genes
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877825001139
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