Offset analgesia a unique paradigm to study pain modulation following 6 weeks of yogic intervention in fibromyalgia patients: A randomized controlled trial
Aim: The aim of this study was to evaluate the effect of supervised yoga therapy on pain modulation through the offset analgesia (OA) paradigm of quantitative sensory testing (QST). Materials and Method: Eighty female FM patients were recruited and randomized into yoga and standard care (SC) groups....
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Yoga-Mimamsa |
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| Online Access: | https://journals.lww.com/10.4103/ym.ym_4_25 |
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| author | Garima Sharma Akanksha Singh Raj Kumar Yadav Uma Kumar Renu Bhatia |
| author_facet | Garima Sharma Akanksha Singh Raj Kumar Yadav Uma Kumar Renu Bhatia |
| author_sort | Garima Sharma |
| collection | DOAJ |
| description | Aim:
The aim of this study was to evaluate the effect of supervised yoga therapy on pain modulation through the offset analgesia (OA) paradigm of quantitative sensory testing (QST).
Materials and Method:
Eighty female FM patients were recruited and randomized into yoga and standard care (SC) groups. Pre- and post-6-week assessments were done for subjective assessment of pain using VAS, widespread pain index, and McGill pain questionnaire-short form. This was followed by thermal assessment (hot pain tolerance threshold) at C8 dermatome of the left forearm to test OA at three randomized sites for 20 patients in each group. OA included experimental trial, repeated OA trial, and downward step test trial. The Normality test was done using the D’Agostino and Pearson normality test. Data found to be normally distributed was compared using paired t-test or Unpaired t-test for within-group and between-group, respectively. Data which did not follow Gaussian distribution was tested using the Wilcoxon signed-rank test or Mann–Whitney test for within-group and between-group, respectively.
Results:
Significance reduction in VAS scores (P<0.05) of pain status was observed after six weeks of yoga intervention. Significant reduction in pain and FM-related symptoms after 6 weeks in FM patients participating in yoga classes was observed. Objective assessment of pain was done using QST (thermal modality) for OA at baseline and 6 weeks. Significant increase in change in VAS minimum (ΔOA), Latency, and OA index was observed after yoga in all the OA paradigms.
Conclusions:
Yoga is an effective complementary therapy for reducing pain and improving quality of life in FM patients after 6 weeks. Additional randomized controlled trials with larger sample sizes are needed to more fully understand this relationship. |
| format | Article |
| id | doaj-art-3cd40525d75644b39f35211ef33c786c |
| institution | DOAJ |
| issn | 0044-0507 2394-2487 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Yoga-Mimamsa |
| spelling | doaj-art-3cd40525d75644b39f35211ef33c786c2025-08-20T03:17:14ZengWolters Kluwer Medknow PublicationsYoga-Mimamsa0044-05072394-24872025-01-01571233310.4103/ym.ym_4_25Offset analgesia a unique paradigm to study pain modulation following 6 weeks of yogic intervention in fibromyalgia patients: A randomized controlled trialGarima SharmaAkanksha SinghRaj Kumar YadavUma KumarRenu BhatiaAim: The aim of this study was to evaluate the effect of supervised yoga therapy on pain modulation through the offset analgesia (OA) paradigm of quantitative sensory testing (QST). Materials and Method: Eighty female FM patients were recruited and randomized into yoga and standard care (SC) groups. Pre- and post-6-week assessments were done for subjective assessment of pain using VAS, widespread pain index, and McGill pain questionnaire-short form. This was followed by thermal assessment (hot pain tolerance threshold) at C8 dermatome of the left forearm to test OA at three randomized sites for 20 patients in each group. OA included experimental trial, repeated OA trial, and downward step test trial. The Normality test was done using the D’Agostino and Pearson normality test. Data found to be normally distributed was compared using paired t-test or Unpaired t-test for within-group and between-group, respectively. Data which did not follow Gaussian distribution was tested using the Wilcoxon signed-rank test or Mann–Whitney test for within-group and between-group, respectively. Results: Significance reduction in VAS scores (P<0.05) of pain status was observed after six weeks of yoga intervention. Significant reduction in pain and FM-related symptoms after 6 weeks in FM patients participating in yoga classes was observed. Objective assessment of pain was done using QST (thermal modality) for OA at baseline and 6 weeks. Significant increase in change in VAS minimum (ΔOA), Latency, and OA index was observed after yoga in all the OA paradigms. Conclusions: Yoga is an effective complementary therapy for reducing pain and improving quality of life in FM patients after 6 weeks. Additional randomized controlled trials with larger sample sizes are needed to more fully understand this relationship.https://journals.lww.com/10.4103/ym.ym_4_25yogaoffset analgesiaquantitative sensory testingfibromyalgiawidespread pain index |
| spellingShingle | Garima Sharma Akanksha Singh Raj Kumar Yadav Uma Kumar Renu Bhatia Offset analgesia a unique paradigm to study pain modulation following 6 weeks of yogic intervention in fibromyalgia patients: A randomized controlled trial Yoga-Mimamsa yoga offset analgesia quantitative sensory testing fibromyalgia widespread pain index |
| title | Offset analgesia a unique paradigm to study pain modulation following 6 weeks of yogic intervention in fibromyalgia patients: A randomized controlled trial |
| title_full | Offset analgesia a unique paradigm to study pain modulation following 6 weeks of yogic intervention in fibromyalgia patients: A randomized controlled trial |
| title_fullStr | Offset analgesia a unique paradigm to study pain modulation following 6 weeks of yogic intervention in fibromyalgia patients: A randomized controlled trial |
| title_full_unstemmed | Offset analgesia a unique paradigm to study pain modulation following 6 weeks of yogic intervention in fibromyalgia patients: A randomized controlled trial |
| title_short | Offset analgesia a unique paradigm to study pain modulation following 6 weeks of yogic intervention in fibromyalgia patients: A randomized controlled trial |
| title_sort | offset analgesia a unique paradigm to study pain modulation following 6 weeks of yogic intervention in fibromyalgia patients a randomized controlled trial |
| topic | yoga offset analgesia quantitative sensory testing fibromyalgia widespread pain index |
| url | https://journals.lww.com/10.4103/ym.ym_4_25 |
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