The relationship between adiposity parameters and C-reactive protein values in overweight and obese women

Background/Aim. Overweight/obesity has become important health problem in developed countries. It may be related to a presence of low-grade inflammation in white adipose tissue. The aim of this study was to investigate the levels of inflammatory marker C-reactive protein (CRP) and its relation to an...

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Main Authors: Mraović Tatjana, Radaković Sonja, Ristić-Medić Danijela, Dinčić Dragan, Tepšić-Ostojić Vesna, Čairović Aleksandra, Miljanović Gora, Rađen Slavica
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2018-01-01
Series:Vojnosanitetski Pregled
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Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600208M.pdf
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author Mraović Tatjana
Radaković Sonja
Ristić-Medić Danijela
Dinčić Dragan
Tepšić-Ostojić Vesna
Čairović Aleksandra
Miljanović Gora
Rađen Slavica
author_facet Mraović Tatjana
Radaković Sonja
Ristić-Medić Danijela
Dinčić Dragan
Tepšić-Ostojić Vesna
Čairović Aleksandra
Miljanović Gora
Rađen Slavica
author_sort Mraović Tatjana
collection DOAJ
description Background/Aim. Overweight/obesity has become important health problem in developed countries. It may be related to a presence of low-grade inflammation in white adipose tissue. The aim of this study was to investigate the levels of inflammatory marker C-reactive protein (CRP) and its relation to anthropometric parameters in overweight and obese females. Methods. This study included 200 apparently healthy, overweight and obese women (18–45 years). Their standard and alternative anthropometric parameters [body mass index (BMI), percentage of fat (%F), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), body adiposity index (BAI)] were determined and correlated to serum CRP concentration. Results. Average CRP level was 5.56 ± 2.43 mg/L, and it significantly positively correlated to all investigated anthropometric parameters. There was significant difference between overweight and obese group in all investigated anthropometric parameters, as well as in CRP values. When investigated separately, according to BMI, values regarding obese females showed significant correlation between CRP and every investigated anthropometric parameter. In overweight subjects, no such correlation was recorded. In the obese group, all investigated parameters were significantly related to F. In overweight subjects, body weight (BW), BMI, WC and WHtR showed significant relation to F. Conclusion. The significant difference between the overweight and obese group in all parameters of central obesity was found as well as in the CRP levels. In the obese group, we found strong correlation between adiposity measured by fat percentage and parameters of central obesity, while in the overweight group WHR and BAI did not correlate to fat percentage. Our results confirmed that CRP is a valuable marker of metabolic risk in obese females, and BMI, although not so new, is still reliable parameter of adiposity.
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spelling doaj-art-3cd2e1b2f3a241ea9a102d33f70006ad2025-08-20T02:16:39ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202018-01-0175218519010.2298/VSP160419208M0042-84501600208MThe relationship between adiposity parameters and C-reactive protein values in overweight and obese womenMraović Tatjana0Radaković Sonja1Ristić-Medić Danijela2Dinčić Dragan3Tepšić-Ostojić Vesna4Čairović Aleksandra5Miljanović Gora6Rađen Slavica7University of Defence, Military Medical Academy, Faculty of Medicine, BelgradeUniversity of Defence, Military Medical Academy, Faculty of Medicine, BelgradeInstitute for Medical Research, Centre of Research Exellence in Nutrition and Metabilism, BelgradeUniversity of Defence, Military Medical Academy, Faculty of Medicine, BelgradeUniversity of Defence, Military Medical Academy, Faculty of Medicine, BelgradeSchool of Dental Medicine, BelgradeMedical College of Vocational Studies, BelgradeUniversity of Defence, Military Medical Academy, Faculty of Medicine, BelgradeBackground/Aim. Overweight/obesity has become important health problem in developed countries. It may be related to a presence of low-grade inflammation in white adipose tissue. The aim of this study was to investigate the levels of inflammatory marker C-reactive protein (CRP) and its relation to anthropometric parameters in overweight and obese females. Methods. This study included 200 apparently healthy, overweight and obese women (18–45 years). Their standard and alternative anthropometric parameters [body mass index (BMI), percentage of fat (%F), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), body adiposity index (BAI)] were determined and correlated to serum CRP concentration. Results. Average CRP level was 5.56 ± 2.43 mg/L, and it significantly positively correlated to all investigated anthropometric parameters. There was significant difference between overweight and obese group in all investigated anthropometric parameters, as well as in CRP values. When investigated separately, according to BMI, values regarding obese females showed significant correlation between CRP and every investigated anthropometric parameter. In overweight subjects, no such correlation was recorded. In the obese group, all investigated parameters were significantly related to F. In overweight subjects, body weight (BW), BMI, WC and WHtR showed significant relation to F. Conclusion. The significant difference between the overweight and obese group in all parameters of central obesity was found as well as in the CRP levels. In the obese group, we found strong correlation between adiposity measured by fat percentage and parameters of central obesity, while in the overweight group WHR and BAI did not correlate to fat percentage. Our results confirmed that CRP is a valuable marker of metabolic risk in obese females, and BMI, although not so new, is still reliable parameter of adiposity.http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600208M.pdfobesityoverweightwomenanthropometryC-rectiveprotein
spellingShingle Mraović Tatjana
Radaković Sonja
Ristić-Medić Danijela
Dinčić Dragan
Tepšić-Ostojić Vesna
Čairović Aleksandra
Miljanović Gora
Rađen Slavica
The relationship between adiposity parameters and C-reactive protein values in overweight and obese women
Vojnosanitetski Pregled
obesity
overweight
women
anthropometry
C-rective
protein
title The relationship between adiposity parameters and C-reactive protein values in overweight and obese women
title_full The relationship between adiposity parameters and C-reactive protein values in overweight and obese women
title_fullStr The relationship between adiposity parameters and C-reactive protein values in overweight and obese women
title_full_unstemmed The relationship between adiposity parameters and C-reactive protein values in overweight and obese women
title_short The relationship between adiposity parameters and C-reactive protein values in overweight and obese women
title_sort relationship between adiposity parameters and c reactive protein values in overweight and obese women
topic obesity
overweight
women
anthropometry
C-rective
protein
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600208M.pdf
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