Feasibility, reliability and validity of smartphone administered cognitive ecological momentary assessments in breast cancer survivors

ObjectiveBreast cancer and its treatment are associated with cancer-related cognitive impairments (CRCI). Cognitive ecological momentary assessments (EMA) allow for the assessment of individual subjective and objective cognitive functioning in real world environments and can be easily administered v...

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Main Authors: Ashley M. Henneghan, Emily W. Paolillo, Kathleen M. Van Dyk, Oscar Y. Franco-Rocha, Mansi Patel, So Hyeon Bang, Raeanne C. Moore
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Digital Health
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Online Access:https://www.frontiersin.org/articles/10.3389/fdgth.2025.1543846/full
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author Ashley M. Henneghan
Ashley M. Henneghan
Emily W. Paolillo
Kathleen M. Van Dyk
Kathleen M. Van Dyk
Oscar Y. Franco-Rocha
Mansi Patel
So Hyeon Bang
Raeanne C. Moore
author_facet Ashley M. Henneghan
Ashley M. Henneghan
Emily W. Paolillo
Kathleen M. Van Dyk
Kathleen M. Van Dyk
Oscar Y. Franco-Rocha
Mansi Patel
So Hyeon Bang
Raeanne C. Moore
author_sort Ashley M. Henneghan
collection DOAJ
description ObjectiveBreast cancer and its treatment are associated with cancer-related cognitive impairments (CRCI). Cognitive ecological momentary assessments (EMA) allow for the assessment of individual subjective and objective cognitive functioning in real world environments and can be easily administered via smartphones. The objective of this study was to establish the feasibility, reliability, and validity of a cognitive EMA platform, NeuroUX, for assessing CRCI in breast cancer survivors.MethodsUsing a prospective design, clinical cognitive assessments (neuropsychological testing; patient reported outcomes) were collected at baseline, followed by an 8-week EMA smartphone protocol assessing self-reported cognitive concerns and objective cognitive performance via mobile cognitive tests once per day, every other day. Satisfaction and feedback questions were included in follow-up data collection. Feasibility data were analyzed using descriptive methods. Test–retest reliability was examined using intraclass correlation coefficients for each cognitive EMA (tests and self-report questions), and Pearson's correlation was used to evaluate convergent validity between cognitive EMAs and baseline clinical cognitive variables.Results105 breast cancer survivors completed the EMA protocol with high adherence (87.3%) and high satisfaction (mean 87%). Intraclass correlation coefficients for all cognitive EMAs were strong (>0.73) and correlational findings indicated moderately strong convergent validity (|0.23| < r < |0.61|).ConclusionFully remote, self-administered cognitive testing for 8-weeks on smartphones was feasible in breast cancer survivors who completed adjuvant treatment and the specific cognitive EMAs (cognitive EMA tests and self-report questions) administered demonstrate strong reliability and validity for CRCI.
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spelling doaj-art-3cbcfebb45a9456bbf05cad5115fbf9e2025-08-20T03:14:51ZengFrontiers Media S.A.Frontiers in Digital Health2673-253X2025-04-01710.3389/fdgth.2025.15438461543846Feasibility, reliability and validity of smartphone administered cognitive ecological momentary assessments in breast cancer survivorsAshley M. Henneghan0Ashley M. Henneghan1Emily W. Paolillo2Kathleen M. Van Dyk3Kathleen M. Van Dyk4Oscar Y. Franco-Rocha5Mansi Patel6So Hyeon Bang7Raeanne C. Moore8School of Nursing, University of Texas at Austin, Austin, TX, United StatesDell Medical School, Department of Oncology, University of Texas at Austin, Austin, TX, United StatesDepartment of Neurology, Memory and Aging Center, University of California, San Francisco, Weill Institute for Neurosciences, San Francisco, CA, United StatesSemel Institute of Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA, United StatesJonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, CA, United StatesSchool of Nursing, University of Texas at Austin, Austin, TX, United StatesDepartment of Neuroscience, College of Natural Sciences, University of Texas at Austin, Austin, TX, United StatesSchool of Nursing, Columbia University, New York, NY, United StatesUC San Diego Health Sciences, University of California San Diego, San Diego, CA, United StatesObjectiveBreast cancer and its treatment are associated with cancer-related cognitive impairments (CRCI). Cognitive ecological momentary assessments (EMA) allow for the assessment of individual subjective and objective cognitive functioning in real world environments and can be easily administered via smartphones. The objective of this study was to establish the feasibility, reliability, and validity of a cognitive EMA platform, NeuroUX, for assessing CRCI in breast cancer survivors.MethodsUsing a prospective design, clinical cognitive assessments (neuropsychological testing; patient reported outcomes) were collected at baseline, followed by an 8-week EMA smartphone protocol assessing self-reported cognitive concerns and objective cognitive performance via mobile cognitive tests once per day, every other day. Satisfaction and feedback questions were included in follow-up data collection. Feasibility data were analyzed using descriptive methods. Test–retest reliability was examined using intraclass correlation coefficients for each cognitive EMA (tests and self-report questions), and Pearson's correlation was used to evaluate convergent validity between cognitive EMAs and baseline clinical cognitive variables.Results105 breast cancer survivors completed the EMA protocol with high adherence (87.3%) and high satisfaction (mean 87%). Intraclass correlation coefficients for all cognitive EMAs were strong (>0.73) and correlational findings indicated moderately strong convergent validity (|0.23| < r < |0.61|).ConclusionFully remote, self-administered cognitive testing for 8-weeks on smartphones was feasible in breast cancer survivors who completed adjuvant treatment and the specific cognitive EMAs (cognitive EMA tests and self-report questions) administered demonstrate strong reliability and validity for CRCI.https://www.frontiersin.org/articles/10.3389/fdgth.2025.1543846/fullecological momentary assessmentsmobile cognitive testingcancer-related cognitive impairmentbreast cancer survivorsreliabilityvalidity
spellingShingle Ashley M. Henneghan
Ashley M. Henneghan
Emily W. Paolillo
Kathleen M. Van Dyk
Kathleen M. Van Dyk
Oscar Y. Franco-Rocha
Mansi Patel
So Hyeon Bang
Raeanne C. Moore
Feasibility, reliability and validity of smartphone administered cognitive ecological momentary assessments in breast cancer survivors
Frontiers in Digital Health
ecological momentary assessments
mobile cognitive testing
cancer-related cognitive impairment
breast cancer survivors
reliability
validity
title Feasibility, reliability and validity of smartphone administered cognitive ecological momentary assessments in breast cancer survivors
title_full Feasibility, reliability and validity of smartphone administered cognitive ecological momentary assessments in breast cancer survivors
title_fullStr Feasibility, reliability and validity of smartphone administered cognitive ecological momentary assessments in breast cancer survivors
title_full_unstemmed Feasibility, reliability and validity of smartphone administered cognitive ecological momentary assessments in breast cancer survivors
title_short Feasibility, reliability and validity of smartphone administered cognitive ecological momentary assessments in breast cancer survivors
title_sort feasibility reliability and validity of smartphone administered cognitive ecological momentary assessments in breast cancer survivors
topic ecological momentary assessments
mobile cognitive testing
cancer-related cognitive impairment
breast cancer survivors
reliability
validity
url https://www.frontiersin.org/articles/10.3389/fdgth.2025.1543846/full
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