Therapeutics of bitter plants from Northeast region of India and their pharmacological and phytochemical perspectives
Natural resources have been used for food and medicine since the beginning of human civilization, and they have always been a low-cost, easily accessible source for individuals. Northeast region of India (NER) represents a significant portion of India's flora and fauna. Marginality, fragility,...
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Elsevier
2025-02-01
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| Series: | Pharmacological Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1043661825000519 |
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| author | Bhaskar Das Bharat Gopalrao Somkuwar Sushil Kumar Chaudhary Evanylla Kharlyngdoh Careen Liza Pakyntein Kishor Basor Jitendra Kumar Shukla Pardeep Kumar Bhardwaj Pulok Kumar Mukherjee |
| author_facet | Bhaskar Das Bharat Gopalrao Somkuwar Sushil Kumar Chaudhary Evanylla Kharlyngdoh Careen Liza Pakyntein Kishor Basor Jitendra Kumar Shukla Pardeep Kumar Bhardwaj Pulok Kumar Mukherjee |
| author_sort | Bhaskar Das |
| collection | DOAJ |
| description | Natural resources have been used for food and medicine since the beginning of human civilization, and they have always been a low-cost, easily accessible source for individuals. Northeast region of India (NER) represents a significant portion of India's flora and fauna. Marginality, fragility, inaccessibility, ethnicity, and cultural diversity thrived in the region, resulting in the richest reservoir of genetic variation of bioresources. Several bitter plants are used by the locals as both food and medicine to treat a variety of diseases. These medicinal plants are an excellent source of chemically diverse biologically active phytometabolites. There have been few efforts to raise awareness about health benefits of bitter plant resources abound in this region that may provides opportunities for their sustainable utilization. Understanding the structural features of plant derived bitterants in relationship with specific bitter receptor will provide research prospects to identify biomolecules with health benefits. In this context the present review is intended to deliver phyto-pharmacological aspects of bitter plant resources of NER together with detailed understanding of possible association between plant derived phytometabolites as bitter agonists with extraoral bitter receptors. |
| format | Article |
| id | doaj-art-3cbb45f5892549bcbbf711e4ac91b9df |
| institution | Kabale University |
| issn | 1096-1186 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pharmacological Research |
| spelling | doaj-art-3cbb45f5892549bcbbf711e4ac91b9df2025-02-08T04:59:55ZengElsevierPharmacological Research1096-11862025-02-01212107626Therapeutics of bitter plants from Northeast region of India and their pharmacological and phytochemical perspectivesBhaskar Das0Bharat Gopalrao Somkuwar1Sushil Kumar Chaudhary2Evanylla Kharlyngdoh3Careen Liza Pakyntein4Kishor Basor5Jitendra Kumar Shukla6Pardeep Kumar Bhardwaj7Pulok Kumar Mukherjee8BRIC-Institute of Bioresources and Sustainable Development (BRIC-IBSD), Department of Biotechnology, Government of India, Imphal, Manipur795001, IndiaBRIC-IBSD, Mizoram Center, Aizawl, Mizoram 796005, IndiaBRIC-IBSD, Meghalaya Center, Shillong, Meghalaya 793009, IndiaBRIC-IBSD, Meghalaya Center, Shillong, Meghalaya 793009, IndiaBRIC-IBSD, Meghalaya Center, Shillong, Meghalaya 793009, IndiaBRIC-IBSD, Meghalaya Center, Shillong, Meghalaya 793009, IndiaBRIC-IBSD, Mizoram Center, Aizawl, Mizoram 796005, IndiaBRIC-IBSD, Meghalaya Center, Shillong, Meghalaya 793009, IndiaBRIC-Institute of Bioresources and Sustainable Development (BRIC-IBSD), Department of Biotechnology, Government of India, Imphal, Manipur795001, India; BRIC-IBSD, Mizoram Center, Aizawl, Mizoram 796005, India; BRIC-IBSD, Meghalaya Center, Shillong, Meghalaya 793009, India; Corresponding author at: BRIC-Institute of Bioresources and Sustainable Development (BRIC-IBSD), Department of Biotechnology, Government of India, Imphal, Manipur 795001, India.Natural resources have been used for food and medicine since the beginning of human civilization, and they have always been a low-cost, easily accessible source for individuals. Northeast region of India (NER) represents a significant portion of India's flora and fauna. Marginality, fragility, inaccessibility, ethnicity, and cultural diversity thrived in the region, resulting in the richest reservoir of genetic variation of bioresources. Several bitter plants are used by the locals as both food and medicine to treat a variety of diseases. These medicinal plants are an excellent source of chemically diverse biologically active phytometabolites. There have been few efforts to raise awareness about health benefits of bitter plant resources abound in this region that may provides opportunities for their sustainable utilization. Understanding the structural features of plant derived bitterants in relationship with specific bitter receptor will provide research prospects to identify biomolecules with health benefits. In this context the present review is intended to deliver phyto-pharmacological aspects of bitter plant resources of NER together with detailed understanding of possible association between plant derived phytometabolites as bitter agonists with extraoral bitter receptors.http://www.sciencedirect.com/science/article/pii/S1043661825000519EthnomedicineBitter taste plantsSecondary metabolitesMetabolic dysregulationTaste physiologyT2Rs agonists |
| spellingShingle | Bhaskar Das Bharat Gopalrao Somkuwar Sushil Kumar Chaudhary Evanylla Kharlyngdoh Careen Liza Pakyntein Kishor Basor Jitendra Kumar Shukla Pardeep Kumar Bhardwaj Pulok Kumar Mukherjee Therapeutics of bitter plants from Northeast region of India and their pharmacological and phytochemical perspectives Pharmacological Research Ethnomedicine Bitter taste plants Secondary metabolites Metabolic dysregulation Taste physiology T2Rs agonists |
| title | Therapeutics of bitter plants from Northeast region of India and their pharmacological and phytochemical perspectives |
| title_full | Therapeutics of bitter plants from Northeast region of India and their pharmacological and phytochemical perspectives |
| title_fullStr | Therapeutics of bitter plants from Northeast region of India and their pharmacological and phytochemical perspectives |
| title_full_unstemmed | Therapeutics of bitter plants from Northeast region of India and their pharmacological and phytochemical perspectives |
| title_short | Therapeutics of bitter plants from Northeast region of India and their pharmacological and phytochemical perspectives |
| title_sort | therapeutics of bitter plants from northeast region of india and their pharmacological and phytochemical perspectives |
| topic | Ethnomedicine Bitter taste plants Secondary metabolites Metabolic dysregulation Taste physiology T2Rs agonists |
| url | http://www.sciencedirect.com/science/article/pii/S1043661825000519 |
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