The Big Yawning: Pathological Yawning as a Symptom of Neuromyelitis Optica Spectrum Disorders
Pathological yawning is rarely observed in cerebral or spinal diseases. A 67-year-old woman was admitted with a seven-day progressive hemisyndrome with left-sided limb ataxia and hypesthesia. The patient yawned with a high frequency, partially in salve-like episodes. MRI showed a cervical myelitis o...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2019/9691863 |
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| author | Veronika Spahlinger Annette Niessen Sebastian Rauer Stefan Krämer Matthias Reinhard |
| author_facet | Veronika Spahlinger Annette Niessen Sebastian Rauer Stefan Krämer Matthias Reinhard |
| author_sort | Veronika Spahlinger |
| collection | DOAJ |
| description | Pathological yawning is rarely observed in cerebral or spinal diseases. A 67-year-old woman was admitted with a seven-day progressive hemisyndrome with left-sided limb ataxia and hypesthesia. The patient yawned with a high frequency, partially in salve-like episodes. MRI showed a cervical myelitis over more than three vertebral segments up to the lower medulla and Aquaporin-4-antibodies were positive (diagnostic criteria for a Neuromyelitis optica spectrum disorder were fulfilled). Under treatment with methylprednisolone, followed by plasmapheresis and immunoadsorption, clinical symptoms were regressive and the frequency of yawning completely normalized. When observing pathological yawning, even in the absence of other cerebral or brainstem symptoms, one should be aware of NMOSD as a possible cause. |
| format | Article |
| id | doaj-art-3cae11bdb65b4c9aba31cafff98cfb26 |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-3cae11bdb65b4c9aba31cafff98cfb262025-02-03T05:54:08ZengWileyCase Reports in Neurological Medicine2090-66682090-66762019-01-01201910.1155/2019/96918639691863The Big Yawning: Pathological Yawning as a Symptom of Neuromyelitis Optica Spectrum DisordersVeronika Spahlinger0Annette Niessen1Sebastian Rauer2Stefan Krämer3Matthias Reinhard4Department of Neurology and Clinical Neurophysiology, Medical Center Esslingen, Academic Teaching Hospital of the University of Tübingen, Tübingen, GermanyDepartment of Neurology and Clinical Neurophysiology, Medical Center Esslingen, Academic Teaching Hospital of the University of Tübingen, Tübingen, GermanyDepartment of Neurology and Neurophysiology, University Medical Center Freiburg, University of Freiburg, Freiburg, GermanyDepartment of Radiology and Nuclear Medicine, Medical Center Esslingen, Academic Teaching Hospital of the University of Tübingen, Tübingen, GermanyDepartment of Neurology and Clinical Neurophysiology, Medical Center Esslingen, Academic Teaching Hospital of the University of Tübingen, Tübingen, GermanyPathological yawning is rarely observed in cerebral or spinal diseases. A 67-year-old woman was admitted with a seven-day progressive hemisyndrome with left-sided limb ataxia and hypesthesia. The patient yawned with a high frequency, partially in salve-like episodes. MRI showed a cervical myelitis over more than three vertebral segments up to the lower medulla and Aquaporin-4-antibodies were positive (diagnostic criteria for a Neuromyelitis optica spectrum disorder were fulfilled). Under treatment with methylprednisolone, followed by plasmapheresis and immunoadsorption, clinical symptoms were regressive and the frequency of yawning completely normalized. When observing pathological yawning, even in the absence of other cerebral or brainstem symptoms, one should be aware of NMOSD as a possible cause.http://dx.doi.org/10.1155/2019/9691863 |
| spellingShingle | Veronika Spahlinger Annette Niessen Sebastian Rauer Stefan Krämer Matthias Reinhard The Big Yawning: Pathological Yawning as a Symptom of Neuromyelitis Optica Spectrum Disorders Case Reports in Neurological Medicine |
| title | The Big Yawning: Pathological Yawning as a Symptom of Neuromyelitis Optica Spectrum Disorders |
| title_full | The Big Yawning: Pathological Yawning as a Symptom of Neuromyelitis Optica Spectrum Disorders |
| title_fullStr | The Big Yawning: Pathological Yawning as a Symptom of Neuromyelitis Optica Spectrum Disorders |
| title_full_unstemmed | The Big Yawning: Pathological Yawning as a Symptom of Neuromyelitis Optica Spectrum Disorders |
| title_short | The Big Yawning: Pathological Yawning as a Symptom of Neuromyelitis Optica Spectrum Disorders |
| title_sort | big yawning pathological yawning as a symptom of neuromyelitis optica spectrum disorders |
| url | http://dx.doi.org/10.1155/2019/9691863 |
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