Analysis and prediction of condylar resorption following orthognathic surgery
Abstract Condylar resorption is a feared complication of orthognathic surgery. This study investigated condylar resorption in a cohort of 200 patients This allowed for a powerful update on incidence and risk factors. 9.5% of patients developed resorption. These patients had on average, 17% volume lo...
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Nature Portfolio
2025-01-01
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| Online Access: | https://doi.org/10.1038/s41598-024-81148-w |
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| author | Pieter-Jan Verhelst Sigrid Janssens Harold Matthews Giacomo Begnoni Peter Claes Eman Shaheen Hilde Peeters Constantinus Politis Reinhilde Jacobs |
| author_facet | Pieter-Jan Verhelst Sigrid Janssens Harold Matthews Giacomo Begnoni Peter Claes Eman Shaheen Hilde Peeters Constantinus Politis Reinhilde Jacobs |
| author_sort | Pieter-Jan Verhelst |
| collection | DOAJ |
| description | Abstract Condylar resorption is a feared complication of orthognathic surgery. This study investigated condylar resorption in a cohort of 200 patients This allowed for a powerful update on incidence and risk factors. 9.5% of patients developed resorption. These patients had on average, 17% volume loss with 3.9 mm ramal height loss and 3.1 mm posterior mandibular displacement. 2% of patients had bilateral resorption. Univariable analysis identified a younger age, a bimaxillary + genioplasty procedure, larger mandibular advancements, upward movements of the distal segment, a higher counterclockwise pitch of the distal segment, smaller preoperative condylar volumes and a higher anterior/posterior lower facial height ratio as risk factors on a patient level. Univariable analysis on a condylar level also identified compressive movements of the ramus and a higher mandibular plane angle as risk factors. Using machine learning for the multivariable analysis, the amount of mandibular advancement was the most important predictor for condylar resorption. There were no differences in preoperative mandibular, ramal or condylar shape between patients with or without resorption. These findings suggest condylar resorption may be more common than thought. Identifying risk factors allows surgical plans to be adjusted to reduce the likelihood of resorption, and patients can be more selectively screened postoperatively. |
| format | Article |
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| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
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| spelling | doaj-art-3c95b63cb8374e8a9b4a96e61334c99f2025-01-05T12:21:24ZengNature PortfolioScientific Reports2045-23222025-01-0115111310.1038/s41598-024-81148-wAnalysis and prediction of condylar resorption following orthognathic surgeryPieter-Jan Verhelst0Sigrid Janssens1Harold Matthews2Giacomo Begnoni3Peter Claes4Eman Shaheen5Hilde Peeters6Constantinus Politis7Reinhilde Jacobs8OMFS IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, KU LeuvenOMFS IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, KU LeuvenDepartment of Human Genetics, KU LeuvenOrthodontics Research Unit, Department of Oral Health Sciences, Faculty of Medicine, KU LeuvenDepartment of Human Genetics, KU LeuvenOMFS IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, KU LeuvenDepartment of Human Genetics, KU LeuvenOMFS IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, KU LeuvenOMFS IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, KU LeuvenAbstract Condylar resorption is a feared complication of orthognathic surgery. This study investigated condylar resorption in a cohort of 200 patients This allowed for a powerful update on incidence and risk factors. 9.5% of patients developed resorption. These patients had on average, 17% volume loss with 3.9 mm ramal height loss and 3.1 mm posterior mandibular displacement. 2% of patients had bilateral resorption. Univariable analysis identified a younger age, a bimaxillary + genioplasty procedure, larger mandibular advancements, upward movements of the distal segment, a higher counterclockwise pitch of the distal segment, smaller preoperative condylar volumes and a higher anterior/posterior lower facial height ratio as risk factors on a patient level. Univariable analysis on a condylar level also identified compressive movements of the ramus and a higher mandibular plane angle as risk factors. Using machine learning for the multivariable analysis, the amount of mandibular advancement was the most important predictor for condylar resorption. There were no differences in preoperative mandibular, ramal or condylar shape between patients with or without resorption. These findings suggest condylar resorption may be more common than thought. Identifying risk factors allows surgical plans to be adjusted to reduce the likelihood of resorption, and patients can be more selectively screened postoperatively.https://doi.org/10.1038/s41598-024-81148-wOrthognathic surgeryCondylar resorptionCondylar remodelingBilateral sagittal split osteotomyTemporomandibular joint |
| spellingShingle | Pieter-Jan Verhelst Sigrid Janssens Harold Matthews Giacomo Begnoni Peter Claes Eman Shaheen Hilde Peeters Constantinus Politis Reinhilde Jacobs Analysis and prediction of condylar resorption following orthognathic surgery Scientific Reports Orthognathic surgery Condylar resorption Condylar remodeling Bilateral sagittal split osteotomy Temporomandibular joint |
| title | Analysis and prediction of condylar resorption following orthognathic surgery |
| title_full | Analysis and prediction of condylar resorption following orthognathic surgery |
| title_fullStr | Analysis and prediction of condylar resorption following orthognathic surgery |
| title_full_unstemmed | Analysis and prediction of condylar resorption following orthognathic surgery |
| title_short | Analysis and prediction of condylar resorption following orthognathic surgery |
| title_sort | analysis and prediction of condylar resorption following orthognathic surgery |
| topic | Orthognathic surgery Condylar resorption Condylar remodeling Bilateral sagittal split osteotomy Temporomandibular joint |
| url | https://doi.org/10.1038/s41598-024-81148-w |
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