Microwave-Assisted Synthesis and Characterization of Iron Oxide Nanoparticles for Advanced Biomedical Sensing Applications
This study focuses on the synthesis and characterization of Superparamagnetic Iron Oxide Nanoparticles (IONPs) with potential biomedical and sensing applications. These nanoparticles are in high demand for their biocompatibility, biodegradability, and superparamagnetic properties. In contrast to tra...
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| Format: | Article |
| Language: | English |
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IEEE
2025-01-01
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| Series: | IEEE Open Journal of Nanotechnology |
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| Online Access: | https://ieeexplore.ieee.org/document/10810447/ |
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| author | Vivek Pratap Singh Chandra Prakash Singh Santosh Kumar Saurabh Kumar Pandey Deepak Punetha |
| author_facet | Vivek Pratap Singh Chandra Prakash Singh Santosh Kumar Saurabh Kumar Pandey Deepak Punetha |
| author_sort | Vivek Pratap Singh |
| collection | DOAJ |
| description | This study focuses on the synthesis and characterization of Superparamagnetic Iron Oxide Nanoparticles (IONPs) with potential biomedical and sensing applications. These nanoparticles are in high demand for their biocompatibility, biodegradability, and superparamagnetic properties. In contrast to traditional high-temperature synthesis methods, microwave-assisted co-precipitation provides notable benefits, such as improved superparamagnetic characteristics, a high surface-to-volume ratio, large surface area, and simplified separation processes. The synthesis process utilized microwave-assisted co-precipitation, and a range of characterization techniques, including XRD, FESEM, VSM, FTIR, and UV-spectroscopy, were employed to assess the properties of the iron oxide nanoparticles. Analysis of the XRD, FTIR, and UV-spectroscopy results confirmed the formation of IONPs, predominantly comprising magnetite (Fe3O4). The microwave-synthesized IONPs exhibited superparamagnetic behavior, featuring an average crystallite size of 9 nm and robust saturation magnetization values (up to 68 emu/g). These attributes render them highly suitable for applications such as MRI contrast agents, thermal mediators in hyperthermia, drug delivery systems, and advanced sensor technologies, including magnetic sensing and biosensing applications, where their high magnetic responsiveness and surface functionalization capabilities can be effectively leveraged. |
| format | Article |
| id | doaj-art-3c82213668864622a7a28c0fa66bf99b |
| institution | Kabale University |
| issn | 2644-1292 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | IEEE |
| record_format | Article |
| series | IEEE Open Journal of Nanotechnology |
| spelling | doaj-art-3c82213668864622a7a28c0fa66bf99b2025-01-09T00:02:53ZengIEEEIEEE Open Journal of Nanotechnology2644-12922025-01-016101510.1109/OJNANO.2024.351486610810447Microwave-Assisted Synthesis and Characterization of Iron Oxide Nanoparticles for Advanced Biomedical Sensing ApplicationsVivek Pratap Singh0https://orcid.org/0000-0001-7206-6023Chandra Prakash Singh1Santosh Kumar2https://orcid.org/0000-0003-4149-0096Saurabh Kumar Pandey3https://orcid.org/0000-0002-5013-6745Deepak Punetha4https://orcid.org/0000-0002-5737-2900Sensors and Optoelectronics Research Group (SORG), Department of Electrical Engineering, IIT, Patna, IndiaSensors and Optoelectronics Research Group (SORG), Department of Electrical Engineering, IIT, Patna, IndiaCentre of Excellence for Nanotechnology, Department of Electronics and Communication Engineering, Koneru Lakshmaiah Education Foundation, Guntur, IndiaSensors and Optoelectronics Research Group (SORG), Department of Electrical Engineering, IIT, Patna, IndiaDepartment of Electronics & Communication Engineering, Motilal Nehru National Institute of Technology, Prayagraj, IndiaThis study focuses on the synthesis and characterization of Superparamagnetic Iron Oxide Nanoparticles (IONPs) with potential biomedical and sensing applications. These nanoparticles are in high demand for their biocompatibility, biodegradability, and superparamagnetic properties. In contrast to traditional high-temperature synthesis methods, microwave-assisted co-precipitation provides notable benefits, such as improved superparamagnetic characteristics, a high surface-to-volume ratio, large surface area, and simplified separation processes. The synthesis process utilized microwave-assisted co-precipitation, and a range of characterization techniques, including XRD, FESEM, VSM, FTIR, and UV-spectroscopy, were employed to assess the properties of the iron oxide nanoparticles. Analysis of the XRD, FTIR, and UV-spectroscopy results confirmed the formation of IONPs, predominantly comprising magnetite (Fe3O4). The microwave-synthesized IONPs exhibited superparamagnetic behavior, featuring an average crystallite size of 9 nm and robust saturation magnetization values (up to 68 emu/g). These attributes render them highly suitable for applications such as MRI contrast agents, thermal mediators in hyperthermia, drug delivery systems, and advanced sensor technologies, including magnetic sensing and biosensing applications, where their high magnetic responsiveness and surface functionalization capabilities can be effectively leveraged.https://ieeexplore.ieee.org/document/10810447/Microwave assisted co-precipitationmagnetizationMRIhyperthermiabiomedical sensingiron oxide |
| spellingShingle | Vivek Pratap Singh Chandra Prakash Singh Santosh Kumar Saurabh Kumar Pandey Deepak Punetha Microwave-Assisted Synthesis and Characterization of Iron Oxide Nanoparticles for Advanced Biomedical Sensing Applications IEEE Open Journal of Nanotechnology Microwave assisted co-precipitation magnetization MRI hyperthermia biomedical sensing iron oxide |
| title | Microwave-Assisted Synthesis and Characterization of Iron Oxide Nanoparticles for Advanced Biomedical Sensing Applications |
| title_full | Microwave-Assisted Synthesis and Characterization of Iron Oxide Nanoparticles for Advanced Biomedical Sensing Applications |
| title_fullStr | Microwave-Assisted Synthesis and Characterization of Iron Oxide Nanoparticles for Advanced Biomedical Sensing Applications |
| title_full_unstemmed | Microwave-Assisted Synthesis and Characterization of Iron Oxide Nanoparticles for Advanced Biomedical Sensing Applications |
| title_short | Microwave-Assisted Synthesis and Characterization of Iron Oxide Nanoparticles for Advanced Biomedical Sensing Applications |
| title_sort | microwave assisted synthesis and characterization of iron oxide nanoparticles for advanced biomedical sensing applications |
| topic | Microwave assisted co-precipitation magnetization MRI hyperthermia biomedical sensing iron oxide |
| url | https://ieeexplore.ieee.org/document/10810447/ |
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