Letter to the editor: radiomics signature for dynamic monitoring of tumor-inflamed microenvironment and immunotherapy response prediction
We read with great interest the article by Bernatowicz et al. Despite the promising findings, we would like to highlight several concerns regarding the methodology and interpretation of the results that warrant further discussion, including the stability of radiomic features across pan-cancer types,...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2025-02-01
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| Series: | Journal for ImmunoTherapy of Cancer |
| Online Access: | https://jitc.bmj.com/content/13/2/e011778.full |
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| _version_ | 1850043699804766208 |
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| author | Shuixing Zhang Yuhao Dong |
| author_facet | Shuixing Zhang Yuhao Dong |
| author_sort | Shuixing Zhang |
| collection | DOAJ |
| description | We read with great interest the article by Bernatowicz et al. Despite the promising findings, we would like to highlight several concerns regarding the methodology and interpretation of the results that warrant further discussion, including the stability of radiomic features across pan-cancer types, the optimal threshold for CT-TIME (tumor immune microenvironment) scores, the biological interpretability of radiomic models, and the survival tail effect of immunotherapy responses. |
| format | Article |
| id | doaj-art-3c81d302814c4e5d8b932a55b6fa7073 |
| institution | DOAJ |
| issn | 2051-1426 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | Journal for ImmunoTherapy of Cancer |
| spelling | doaj-art-3c81d302814c4e5d8b932a55b6fa70732025-08-20T02:55:10ZengBMJ Publishing GroupJournal for ImmunoTherapy of Cancer2051-14262025-02-0113210.1136/jitc-2025-011778Letter to the editor: radiomics signature for dynamic monitoring of tumor-inflamed microenvironment and immunotherapy response predictionShuixing Zhang0Yuhao Dong1Radiology, Jinan University First Affiliated Hospital, Guangzhou, Guangdong, ChinaRadiology, Jinan University First Affiliated Hospital, Guangzhou, Guangdong, ChinaWe read with great interest the article by Bernatowicz et al. Despite the promising findings, we would like to highlight several concerns regarding the methodology and interpretation of the results that warrant further discussion, including the stability of radiomic features across pan-cancer types, the optimal threshold for CT-TIME (tumor immune microenvironment) scores, the biological interpretability of radiomic models, and the survival tail effect of immunotherapy responses.https://jitc.bmj.com/content/13/2/e011778.full |
| spellingShingle | Shuixing Zhang Yuhao Dong Letter to the editor: radiomics signature for dynamic monitoring of tumor-inflamed microenvironment and immunotherapy response prediction Journal for ImmunoTherapy of Cancer |
| title | Letter to the editor: radiomics signature for dynamic monitoring of tumor-inflamed microenvironment and immunotherapy response prediction |
| title_full | Letter to the editor: radiomics signature for dynamic monitoring of tumor-inflamed microenvironment and immunotherapy response prediction |
| title_fullStr | Letter to the editor: radiomics signature for dynamic monitoring of tumor-inflamed microenvironment and immunotherapy response prediction |
| title_full_unstemmed | Letter to the editor: radiomics signature for dynamic monitoring of tumor-inflamed microenvironment and immunotherapy response prediction |
| title_short | Letter to the editor: radiomics signature for dynamic monitoring of tumor-inflamed microenvironment and immunotherapy response prediction |
| title_sort | letter to the editor radiomics signature for dynamic monitoring of tumor inflamed microenvironment and immunotherapy response prediction |
| url | https://jitc.bmj.com/content/13/2/e011778.full |
| work_keys_str_mv | AT shuixingzhang lettertotheeditorradiomicssignaturefordynamicmonitoringoftumorinflamedmicroenvironmentandimmunotherapyresponseprediction AT yuhaodong lettertotheeditorradiomicssignaturefordynamicmonitoringoftumorinflamedmicroenvironmentandimmunotherapyresponseprediction |