Evaluation of Microsatellite Instability via High-Resolution Melt Analysis in Colorectal Carcinomas

Evaluation of Microsatellite Instability via High-Resolution Melt Analysis in Colorectal Carcinomas

Background/Objectives: Colorectal cancer (CRC) is the third leading cause of cancer death globally, with rising incidence. The immunohistochemistry (IHC) for mismatch repair (MMR) proteins is the first technique used in routine practice to evaluate an MMR status. Microsatellite instability (MSI) may...

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Main Authors: Thais Maloberti, Sara Coluccelli, Viviana Sanza, Elisa Gruppioni, Annalisa Altimari, Stefano Zagnoni, Lidia Merlo, Antonietta D’Errico, Michelangelo Fiorentino, Daniela Turchetti, Sara Miccoli, Giovanni Tallini, Antonio De Leo, Dario de Biase
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Journal of Molecular Pathology
Subjects:
MSI
colorectal carcinomas
microsatellites
fragment length analysis
high resolution melt
Online Access:https://www.mdpi.com/2673-5261/5/4/34
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