A forward genetic screen reveals that calcium-dependent protein kinase 3 regulates egress in Toxoplasma.

Egress from the host cell is a crucial and highly regulated step in the biology of the obligate intracellular parasite, Toxoplasma gondii. Active egress depends on calcium fluxes and appears to be a crucial step in escaping the attack from the immune system and, potentially, in enabling the parasite...

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Bibliographic Details
Main Authors: Erin Garrison, Moritz Treeck, Emma Ehret, Heidi Butz, Tamila Garbuz, Benji P Oswald, Matt Settles, John Boothroyd, Gustavo Arrizabalaga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003049&type=printable
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