Palmitoleic acid inhibits Pseudomonas aeruginosa quorum sensing activation and protects lungs from infectious injury

Palmitoleic acid inhibits Pseudomonas aeruginosa quorum sensing activation and protects lungs from infectious injury

Abstract Background Unsaturated fatty acids targeting quorum sensing (QS) system have shown potential application in reducing bacterial virulence. We aim to investigate the effect of palmitoleic acid (PMA) on P. aeruginosa QS activation, and its impact on infection-induced lung injury. Methods The i...

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Bibliographic Details
Main Authors: Lei Han, Jie Ren, Yishu Xue, Guogang Xie, Jianwei Gao, Qiang Fu, Ping Shao, Hui Zhu, Min Zhang, Fengming Ding
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Respiratory Research
Subjects:
Palmitoleic acid
Pseudomonas aeruginosa
Quorum sensing
Lung infection
Infection-induced injury
Online Access:https://doi.org/10.1186/s12931-024-03035-2
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