The Controversy of Intraperitoneal Hyperthermic Chemotherapy for Ovarian Cancer

Although the standard treatment for ovarian carcinoma with peritoneal metastases is systemic chemotherapy alone or systemic chemotherapy with debulking surgery, a new technique gains more ground: a combination of hipertermic intraperitoneal chemotherapy (HIPEC) and optimal cytoreduction surgery. The...

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Bibliographic Details
Main Authors: Lucian ALECU, Adrian TULIN, Iulian SLAVU, Cristina ORLOV-SLAVU, Bogdan SOCEA, Cornelia NITIPIR
Format: Article
Language:English
Published: Bucharest College of Physicians 2020-12-01
Series:Modern Medicine
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Online Access:https://medicinamoderna.ro/wp-content/uploads/2020/12/RMM_art-2.pdf
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Summary:Although the standard treatment for ovarian carcinoma with peritoneal metastases is systemic chemotherapy alone or systemic chemotherapy with debulking surgery, a new technique gains more ground: a combination of hipertermic intraperitoneal chemotherapy (HIPEC) and optimal cytoreduction surgery. The proof is mounting regarding the benefits of HIPEC for patients with metastatic ovarian carcinoma but it still lacks a standard protocol of use. It has increased costs, and incomplete data regarding its safety. Due to these reasons, it is still considered an alternative treatment. Our study aimed to evaluate the published literature regarding this technique from the point of view of safety and efficacy when compared with the standard of care treatment.
ISSN:1223-0472
2360-2473