Metabolomic analysis reveals trimethylamine N-oxide as a biomarker for poor outcome of severe spontaneous intracerebral hemorrhage patients receiving surgical treatment

Metabolomic analysis reveals trimethylamine N-oxide as a biomarker for poor outcome of severe spontaneous intracerebral hemorrhage patients receiving surgical treatment

Background and objectivesPatients suffering from severe spontaneous intracerebral hemorrhage (SSICH) are at high risk of cardiocerebrovascular diseases postoperatively, which hugely affect patients’ long-term outcomes. Metabolic features could reflect the pathological change of the cardiocerebrovasc...

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Bibliographic Details
Main Authors: Xinguo Sun, Kaige Zheng, Shanjun Wang, Yunzhao Chen, Hongen Liu, Xindong Gu, Zitong Wu, Hui Lu, Shuo Wang, Qingyuan Liu, Zengguang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Neurology
Subjects:
spontaneous intracerebral hemorrhage
surgical treatment
poor outcome
metabolomic analysis
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1551239/full
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