Spatial transcriptomics identifies RBM39 as a gene associated with Gleason score progression in prostate cancer

Spatial transcriptomics identifies RBM39 as a gene associated with Gleason score progression in prostate cancer

Summary: Prostate cancer (PCa) exhibits significant intratumor heterogeneity, frequently manifesting as a multifocal disease. This study utilized Visium spatial transcriptomics (ST) to explore transcriptome patterns in PCa regions with varying Gleason scores (GSs). Principal component analysis (PCA)...

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Bibliographic Details
Main Authors: Yongjun Quan, Mingdong Wang, Hong Zhang, Dan Lu, Hao Ping
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Health sciences
Medicine
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224025768
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