Analysis of Human Kidney Stones Using Advanced Characterization Techniques
A comprehensive analysis of kidney stones is essential for the future treatment of patients. Almost all of the methods available for kidney stone analysis were used in this study. The chemical analysis included powder X-ray diffraction (PXRD), Fourier transform infrared spectroscopy (FTIR), and ther...
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2024-12-01
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| Series: | Crystals |
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| author | Jelena Brdarić Kosanović Kristijan Živković Vatroslav Šerić Berislav Marković Imre Szenti Ákos Kukovecz Nives Matijaković Mlinarić Anamarija Stanković |
| author_facet | Jelena Brdarić Kosanović Kristijan Živković Vatroslav Šerić Berislav Marković Imre Szenti Ákos Kukovecz Nives Matijaković Mlinarić Anamarija Stanković |
| author_sort | Jelena Brdarić Kosanović |
| collection | DOAJ |
| description | A comprehensive analysis of kidney stones is essential for the future treatment of patients. Almost all of the methods available for kidney stone analysis were used in this study. The chemical analysis included powder X-ray diffraction (PXRD), Fourier transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA-DSC). Following the chemical analysis, a detailed morphological analysis was carried out using stereoscopic microscopy, scanning electron microscopy (SEM-EDX), and micro-computed tomography (micro-CT). These investigations showed that the sixteen kidney stones analyzed in detail had a heterogeneous mineralogical structure, consisting of at least two different minerals. Kidney stones consist mainly of calcium oxalate (whewellite or weddellite) but also contain significant amounts of phosphate (mainly apatite and struvite). A thorough analysis of kidney stones can determine the cause of their formation and investigate possible treatments. |
| format | Article |
| id | doaj-art-3c4c35843cf042ad85d829ecbf3f6cef |
| institution | Kabale University |
| issn | 2073-4352 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Crystals |
| spelling | doaj-art-3c4c35843cf042ad85d829ecbf3f6cef2025-01-24T13:27:59ZengMDPI AGCrystals2073-43522024-12-01151610.3390/cryst15010006Analysis of Human Kidney Stones Using Advanced Characterization TechniquesJelena Brdarić Kosanović0Kristijan Živković1Vatroslav Šerić2Berislav Marković3Imre Szenti4Ákos Kukovecz5Nives Matijaković Mlinarić6Anamarija Stanković7Department of Chemistry, University of Osijek, Cara Hadrijana 8/A, 31000 Osijek, CroatiaDepartment of Chemistry, University of Osijek, Cara Hadrijana 8/A, 31000 Osijek, CroatiaClinical Institute for Laboratory Diagnostics, University Hospital Osijek, 31000 Osijek, CroatiaFaculty of Dental Medicine and Health Osijek, Crkvena 21, 31000 Osijek, CroatiaDepartment of Applied and Environmental Chemistry, University of Szeged, Rerich Béla tér 1, H-6720 Szeged, HungaryDepartment of Applied and Environmental Chemistry, University of Szeged, Rerich Béla tér 1, H-6720 Szeged, HungaryRuđer Bošković Institute, Bijenička pregledali smo sta 54, 10000 Zagreb, CroatiaDepartment of Chemistry, University of Osijek, Cara Hadrijana 8/A, 31000 Osijek, CroatiaA comprehensive analysis of kidney stones is essential for the future treatment of patients. Almost all of the methods available for kidney stone analysis were used in this study. The chemical analysis included powder X-ray diffraction (PXRD), Fourier transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA-DSC). Following the chemical analysis, a detailed morphological analysis was carried out using stereoscopic microscopy, scanning electron microscopy (SEM-EDX), and micro-computed tomography (micro-CT). These investigations showed that the sixteen kidney stones analyzed in detail had a heterogeneous mineralogical structure, consisting of at least two different minerals. Kidney stones consist mainly of calcium oxalate (whewellite or weddellite) but also contain significant amounts of phosphate (mainly apatite and struvite). A thorough analysis of kidney stones can determine the cause of their formation and investigate possible treatments.https://www.mdpi.com/2073-4352/15/1/6kidney stonescalcium oxalatephosphatechemical analysis |
| spellingShingle | Jelena Brdarić Kosanović Kristijan Živković Vatroslav Šerić Berislav Marković Imre Szenti Ákos Kukovecz Nives Matijaković Mlinarić Anamarija Stanković Analysis of Human Kidney Stones Using Advanced Characterization Techniques Crystals kidney stones calcium oxalate phosphate chemical analysis |
| title | Analysis of Human Kidney Stones Using Advanced Characterization Techniques |
| title_full | Analysis of Human Kidney Stones Using Advanced Characterization Techniques |
| title_fullStr | Analysis of Human Kidney Stones Using Advanced Characterization Techniques |
| title_full_unstemmed | Analysis of Human Kidney Stones Using Advanced Characterization Techniques |
| title_short | Analysis of Human Kidney Stones Using Advanced Characterization Techniques |
| title_sort | analysis of human kidney stones using advanced characterization techniques |
| topic | kidney stones calcium oxalate phosphate chemical analysis |
| url | https://www.mdpi.com/2073-4352/15/1/6 |
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