Some pro- and anti-inflammatory cytokines, their genetic polymorphism and postinfarct cardiac remodeling
The role of molecular genetic factors in cardiovascular disease (CVD) development has been actively studied in recent years. In patients with acute myocardial infarction and heart failure, the genetic component contributes to the determination of inflammation and persistence of inflammatory mediator...
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2020-11-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/4007 |
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| author | A. M. Nikolaeva N. P. Babushkina V. V. Ryabov |
| author_facet | A. M. Nikolaeva N. P. Babushkina V. V. Ryabov |
| author_sort | A. M. Nikolaeva |
| collection | DOAJ |
| description | The role of molecular genetic factors in cardiovascular disease (CVD) development has been actively studied in recent years. In patients with acute myocardial infarction and heart failure, the genetic component contributes to the determination of inflammation and persistence of inflammatory mediators in the myocardium. The genetic component in combination with traditional CVD risk factors determines the clinical course of the disease, the severity and its outcome. This review summarizes the data on relationship of proand anti-inflammatory cytokines with coronary artery disease and its clinical manifestations. |
| format | Article |
| id | doaj-art-3c3e83f6d13f4b79b3208a09ab69a0e1 |
| institution | Kabale University |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| publishDate | 2020-11-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj-art-3c3e83f6d13f4b79b3208a09ab69a0e12025-08-20T03:57:26Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202020-11-01251010.15829/1560-4071-2020-40073059Some pro- and anti-inflammatory cytokines, their genetic polymorphism and postinfarct cardiac remodelingA. M. Nikolaeva0N. P. Babushkina1V. V. Ryabov2Cardiology Research Institute, Tomsk National Research Medical CenterResearch Institute of Medical Genetics, Tomsk National Research Medical CenterCardiology Research Institute, Tomsk National Research Medical Center; National Research Tomsk State University; Siberian State Medical UniversityThe role of molecular genetic factors in cardiovascular disease (CVD) development has been actively studied in recent years. In patients with acute myocardial infarction and heart failure, the genetic component contributes to the determination of inflammation and persistence of inflammatory mediators in the myocardium. The genetic component in combination with traditional CVD risk factors determines the clinical course of the disease, the severity and its outcome. This review summarizes the data on relationship of proand anti-inflammatory cytokines with coronary artery disease and its clinical manifestations.https://russjcardiol.elpub.ru/jour/article/view/4007myocardial infarctionheart failuregenetic polymorphismcytokinesangiogenic growth factorspostinfarct cardiac remodeling |
| spellingShingle | A. M. Nikolaeva N. P. Babushkina V. V. Ryabov Some pro- and anti-inflammatory cytokines, their genetic polymorphism and postinfarct cardiac remodeling Российский кардиологический журнал myocardial infarction heart failure genetic polymorphism cytokines angiogenic growth factors postinfarct cardiac remodeling |
| title | Some pro- and anti-inflammatory cytokines, their genetic polymorphism and postinfarct cardiac remodeling |
| title_full | Some pro- and anti-inflammatory cytokines, their genetic polymorphism and postinfarct cardiac remodeling |
| title_fullStr | Some pro- and anti-inflammatory cytokines, their genetic polymorphism and postinfarct cardiac remodeling |
| title_full_unstemmed | Some pro- and anti-inflammatory cytokines, their genetic polymorphism and postinfarct cardiac remodeling |
| title_short | Some pro- and anti-inflammatory cytokines, their genetic polymorphism and postinfarct cardiac remodeling |
| title_sort | some pro and anti inflammatory cytokines their genetic polymorphism and postinfarct cardiac remodeling |
| topic | myocardial infarction heart failure genetic polymorphism cytokines angiogenic growth factors postinfarct cardiac remodeling |
| url | https://russjcardiol.elpub.ru/jour/article/view/4007 |
| work_keys_str_mv | AT amnikolaeva someproandantiinflammatorycytokinestheirgeneticpolymorphismandpostinfarctcardiacremodeling AT npbabushkina someproandantiinflammatorycytokinestheirgeneticpolymorphismandpostinfarctcardiacremodeling AT vvryabov someproandantiinflammatorycytokinestheirgeneticpolymorphismandpostinfarctcardiacremodeling |