Intensive critical care and management of asthmatic and smoker patients in COVID-19 infection

This century’s most serious catastrophe, COVID-19, has been dubbed “the most life-threatening disaster ever”. Asthmatic persons are even more prone to COVID-19’s complex interplay with the underlying inflammatory condition. In order to protect themselves against COVID-19, asthmatic patients must be...

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Main Authors: Lu Dongming, Yaqoob Obaid, Kumar Manish, Kushwah Ajay Singh, Sharma Rahul Kumar, Kumar Devinder, Mavai Yogendra, Khan Rukaiya
Format: Article
Language:English
Published: Sciendo 2023-03-01
Series:Acta Pharmaceutica
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Online Access:https://doi.org/10.2478/acph-2023-0002
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author Lu Dongming
Yaqoob Obaid
Kumar Manish
Kushwah Ajay Singh
Sharma Rahul Kumar
Kumar Devinder
Mavai Yogendra
Khan Rukaiya
author_facet Lu Dongming
Yaqoob Obaid
Kumar Manish
Kushwah Ajay Singh
Sharma Rahul Kumar
Kumar Devinder
Mavai Yogendra
Khan Rukaiya
author_sort Lu Dongming
collection DOAJ
description This century’s most serious catastrophe, COVID-19, has been dubbed “the most life-threatening disaster ever”. Asthmatic persons are even more prone to COVID-19’s complex interplay with the underlying inflammatory condition. In order to protect themselves against COVID-19, asthmatic patients must be very vigilant in their usage of therapeutic techniques and drugs (e.g., bronchodilators, 5-lipoxygenase inhibitors), which may be accessed to deal with mild, moderate, and severe COVID-19 indications. People with asthma may have more severe COVID-19 symptoms, which may lead to a worsening of their condition. Several cytokines were found to be elevated in the bronchial tracts of patients with acute instances of COVID-19, suggesting that this ailment may aggravate asthma episodes by increasing inflammation. The intensity of COVID-19 symptoms is lessened in patients with asthma who have superior levels of T-cells. Several antibiotics, antivirals, antipyretics, and anti-inflammatory drugs have been suggested to suppress COVID-19 symptoms in asthmatic persons. Furthermore, smokers are more likely to have aggravated repercussions in COVID-19 infection. Being hospitalized to critical care due to COVID-19, needing mechanical breathing, and suffering from serious health repercussions, are all possible outcomes for someone who has previously smoked. Smoking damages airways and alveoli, which significantly raises the risk of COVID-19-related health complications. Patients with a previous record of smoking are predisposed to severe COVID-19 disease symptoms that essentially require a combination of bronchodilators, mucolytics, antivirals, and antimuscarinic drugs, to cope with the situation. The present review discusses the care and management of asthmatic and smoker patients in COVID-19 infection.
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spelling doaj-art-3c36ee230c054c37943a477a433495882025-02-03T07:26:16ZengSciendoActa Pharmaceutica1846-95582023-03-01731294210.2478/acph-2023-0002Intensive critical care and management of asthmatic and smoker patients in COVID-19 infectionLu Dongming0Yaqoob Obaid1Kumar Manish2Kushwah Ajay Singh3Sharma Rahul Kumar4Kumar Devinder5Mavai Yogendra6Khan Rukaiya7Department of Pulmonary and Critical Care Medicine, Jinling Hospital Nanjing University School of Medicine Nanjing, Jiangsu, 210000, ChinaDepartment of Pharmacology, Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy, Bela (An Autonomous College), Ropar, Punjab 140111, IndiaChitkara College of Pharmacy, Chitkara University, Punjab, 140401, IndiaDepartment of Pharmacology, Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy, Bela (An Autonomous College), Ropar, Punjab 140111, IndiaDepartment of Pharmacology, Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy, Bela (An Autonomous College), Ropar, Punjab 140111, IndiaDepartment of Pharmacology, Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy, Bela (An Autonomous College), Ropar, Punjab 140111, IndiaIPS College of Pharmacy, Shivpuri Link Road Gwalior, M.P., 474001, IndiaAbhilashi College of Pharmacy, Nerchowk Mandi, H.P., 175008, IndiaThis century’s most serious catastrophe, COVID-19, has been dubbed “the most life-threatening disaster ever”. Asthmatic persons are even more prone to COVID-19’s complex interplay with the underlying inflammatory condition. In order to protect themselves against COVID-19, asthmatic patients must be very vigilant in their usage of therapeutic techniques and drugs (e.g., bronchodilators, 5-lipoxygenase inhibitors), which may be accessed to deal with mild, moderate, and severe COVID-19 indications. People with asthma may have more severe COVID-19 symptoms, which may lead to a worsening of their condition. Several cytokines were found to be elevated in the bronchial tracts of patients with acute instances of COVID-19, suggesting that this ailment may aggravate asthma episodes by increasing inflammation. The intensity of COVID-19 symptoms is lessened in patients with asthma who have superior levels of T-cells. Several antibiotics, antivirals, antipyretics, and anti-inflammatory drugs have been suggested to suppress COVID-19 symptoms in asthmatic persons. Furthermore, smokers are more likely to have aggravated repercussions in COVID-19 infection. Being hospitalized to critical care due to COVID-19, needing mechanical breathing, and suffering from serious health repercussions, are all possible outcomes for someone who has previously smoked. Smoking damages airways and alveoli, which significantly raises the risk of COVID-19-related health complications. Patients with a previous record of smoking are predisposed to severe COVID-19 disease symptoms that essentially require a combination of bronchodilators, mucolytics, antivirals, and antimuscarinic drugs, to cope with the situation. The present review discusses the care and management of asthmatic and smoker patients in COVID-19 infection.https://doi.org/10.2478/acph-2023-0002covid-19asthmasmokingcritical caresars-cov-2
spellingShingle Lu Dongming
Yaqoob Obaid
Kumar Manish
Kushwah Ajay Singh
Sharma Rahul Kumar
Kumar Devinder
Mavai Yogendra
Khan Rukaiya
Intensive critical care and management of asthmatic and smoker patients in COVID-19 infection
Acta Pharmaceutica
covid-19
asthma
smoking
critical care
sars-cov-2
title Intensive critical care and management of asthmatic and smoker patients in COVID-19 infection
title_full Intensive critical care and management of asthmatic and smoker patients in COVID-19 infection
title_fullStr Intensive critical care and management of asthmatic and smoker patients in COVID-19 infection
title_full_unstemmed Intensive critical care and management of asthmatic and smoker patients in COVID-19 infection
title_short Intensive critical care and management of asthmatic and smoker patients in COVID-19 infection
title_sort intensive critical care and management of asthmatic and smoker patients in covid 19 infection
topic covid-19
asthma
smoking
critical care
sars-cov-2
url https://doi.org/10.2478/acph-2023-0002
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