Strain background interacts with chromosome 7 aneuploidy to determine commensal and virulence phenotypes in Candida albicans.

Strain background interacts with chromosome 7 aneuploidy to determine commensal and virulence phenotypes in Candida albicans.

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The human fungal pathobiont Candida albicans displays extensive genomic plasticity, including large-scale chromosomal changes such as aneuploidy. Chromosome trisomy appears frequently in natural and laboratory strains of C. albicans. Trisomy of specific chromosomes has been linked to large phenotypi...

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Bibliographic Details
Main Authors: Abhishek Mishra, Norma V Solis, Siobhan M Dietz, Audra L Crouch, Scott G Filler, Matthew Z Anderson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011650
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