Large Language Models for Transforming Healthcare: A Perspective on DeepSeek‐R1

ABSTRACT DeepSeek‐R1 is an open‐source Large Language Model (LLM) with advanced reasoning capabilities. It has gained significant attention for its impressive advantages including low costs and visualized reasoning steps. Recent advancements in reasoning LLMs like ChatGPT‐o1 have significantly exhib...

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Main Authors: Jinsong Zhou, Yuhan Cheng, Sixu He, Yingcong Chen, Hao Chen
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:MedComm – Future Medicine
Subjects:
Online Access:https://doi.org/10.1002/mef2.70021
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author Jinsong Zhou
Yuhan Cheng
Sixu He
Yingcong Chen
Hao Chen
author_facet Jinsong Zhou
Yuhan Cheng
Sixu He
Yingcong Chen
Hao Chen
author_sort Jinsong Zhou
collection DOAJ
description ABSTRACT DeepSeek‐R1 is an open‐source Large Language Model (LLM) with advanced reasoning capabilities. It has gained significant attention for its impressive advantages including low costs and visualized reasoning steps. Recent advancements in reasoning LLMs like ChatGPT‐o1 have significantly exhibited their considerable reasoning potential, but the closed‐source nature of existing models limits customization and transparency, presenting substantial barriers to their integration into healthcare systems. This gap motivates the exploration of DeepSeek‐R1 in the medical field. Thus, we comprehensively review the transformative potential, applications, and challenges of DeepSeek‐R1 in healthcare. Specifically, we investigate how DeepSeek‐R1 can enhance clinical decision support, patient engagement, and medical education to help for clinic, outpatient and medical research. Furthermore, we critically evaluate challenges including modality limitations (text‐only), hallucination risks, and ethical issues, particularly related to patient autonomy and safety‐focused recommendations. By assessing DeepSeek‐R1′s integration potential, this perspective highlights promising opportunities for advancing medical AI while emphasizing necessary improvements to maximize clinical reliability and ethical compliance. This paper provides valuable guidance for future research directions and elucidates practical application scenarios for DeepSeek‐R1′s successful integration into healthcare settings.
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spelling doaj-art-3c29403cd82f4123b5bc93061ac10ea42025-08-20T03:32:24ZengWileyMedComm – Future Medicine2769-64562025-06-0142n/an/a10.1002/mef2.70021Large Language Models for Transforming Healthcare: A Perspective on DeepSeek‐R1Jinsong Zhou0Yuhan Cheng1Sixu He2Yingcong Chen3Hao Chen4AI Thrust, Information Hub The Hong Kong University of Science and Technology (Guangzhou) Guangzhou Guangdong ChinaAI Thrust, Information Hub The Hong Kong University of Science and Technology (Guangzhou) Guangzhou Guangdong ChinaAI Thrust, Information Hub The Hong Kong University of Science and Technology (Guangzhou) Guangzhou Guangdong ChinaAI Thrust, Information Hub The Hong Kong University of Science and Technology (Guangzhou) Guangzhou Guangdong ChinaDepartment of Computer Science and Engineering The Hong Kong University of Science and Technology Hong Kong ChinaABSTRACT DeepSeek‐R1 is an open‐source Large Language Model (LLM) with advanced reasoning capabilities. It has gained significant attention for its impressive advantages including low costs and visualized reasoning steps. Recent advancements in reasoning LLMs like ChatGPT‐o1 have significantly exhibited their considerable reasoning potential, but the closed‐source nature of existing models limits customization and transparency, presenting substantial barriers to their integration into healthcare systems. This gap motivates the exploration of DeepSeek‐R1 in the medical field. Thus, we comprehensively review the transformative potential, applications, and challenges of DeepSeek‐R1 in healthcare. Specifically, we investigate how DeepSeek‐R1 can enhance clinical decision support, patient engagement, and medical education to help for clinic, outpatient and medical research. Furthermore, we critically evaluate challenges including modality limitations (text‐only), hallucination risks, and ethical issues, particularly related to patient autonomy and safety‐focused recommendations. By assessing DeepSeek‐R1′s integration potential, this perspective highlights promising opportunities for advancing medical AI while emphasizing necessary improvements to maximize clinical reliability and ethical compliance. This paper provides valuable guidance for future research directions and elucidates practical application scenarios for DeepSeek‐R1′s successful integration into healthcare settings.https://doi.org/10.1002/mef2.70021AI for healthcareAI interpretabilitydata privacyDeepSeek‐R1diagnosis and treatmentethics
spellingShingle Jinsong Zhou
Yuhan Cheng
Sixu He
Yingcong Chen
Hao Chen
Large Language Models for Transforming Healthcare: A Perspective on DeepSeek‐R1
MedComm – Future Medicine
AI for healthcare
AI interpretability
data privacy
DeepSeek‐R1
diagnosis and treatment
ethics
title Large Language Models for Transforming Healthcare: A Perspective on DeepSeek‐R1
title_full Large Language Models for Transforming Healthcare: A Perspective on DeepSeek‐R1
title_fullStr Large Language Models for Transforming Healthcare: A Perspective on DeepSeek‐R1
title_full_unstemmed Large Language Models for Transforming Healthcare: A Perspective on DeepSeek‐R1
title_short Large Language Models for Transforming Healthcare: A Perspective on DeepSeek‐R1
title_sort large language models for transforming healthcare a perspective on deepseek r1
topic AI for healthcare
AI interpretability
data privacy
DeepSeek‐R1
diagnosis and treatment
ethics
url https://doi.org/10.1002/mef2.70021
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