Trastuzumab Induces Apoptosis and Cell Cycle Arrest in Triple-Negative Breast Cancer, Suggesting Repurposing Potential

Trastuzumab Induces Apoptosis and Cell Cycle Arrest in Triple-Negative Breast Cancer, Suggesting Repurposing Potential

Background: Breast cancer remains the most common invasive cancer in women worldwide. Triple-negative breast cancer (TNBC) is an aggressive subtype with limited treatment options. Trastuzumab (Tz) is typically used to treat HER2-positive breast cancers, but its potential in TNBC is unclear. Objectiv...

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Main Authors: Shaimaa Abdel-Ghany, Yasmin Khalid, Soha Mohamed, Gehan Mohamed, Engy Mohdy, Abeer Ezzat, Engy F Madian, Osama A Said, Mohamed A Abdel-Hakeem, Mahmoud Nazih, Ahmed Khoder, Hussein Sabit
Format: Article
Language:English
Published: SAGE Publishing 2024-11-01
Series:Breast Cancer: Basic and Clinical Research
Online Access:https://doi.org/10.1177/11782234241285411
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