Promising New Treatments for Psoriasis

Psoriasis is a chronic, proliferative, and inflammatory skin disease affecting 2-3% of the population and is characterized by red plaques with white scales. Psoriasis is a disease that can affect many aspects of professional and social life. Currently, several treatments are available to help contro...

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Main Authors: Sarah Dubois Declercq, Roxane Pouliot
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2013/980419
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author Sarah Dubois Declercq
Roxane Pouliot
author_facet Sarah Dubois Declercq
Roxane Pouliot
author_sort Sarah Dubois Declercq
collection DOAJ
description Psoriasis is a chronic, proliferative, and inflammatory skin disease affecting 2-3% of the population and is characterized by red plaques with white scales. Psoriasis is a disease that can affect many aspects of professional and social life. Currently, several treatments are available to help control psoriasis such as methotrexate, ciclosporin, and oral retinoids. However, the available treatments are only able to relieve the symptoms and lives of individuals. The discovery of new immunological factors and a better understanding of psoriasis have turned to the use of immunological pathways and could develop new biological drugs against specific immunological elements that cause psoriasis. Biological drugs are less toxic to the body and more effective than traditional therapies. Thus, they should improve the quality of life of patients with psoriasis. This review describes new psoriasis treatments, which are on the market or currently in clinical trials that are being used to treat moderate-to-severe plaque psoriasis. In addition, this paper describes the characteristics and mechanisms in detail. In general, biological drugs are well tolerated and appear to be an effective alternative to conventional therapies. However, their effectiveness and long-term side effects need to be further researched.
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spelling doaj-art-3c18672cf3d04c3181d45778a65a8f702025-02-03T01:29:16ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/980419980419Promising New Treatments for PsoriasisSarah Dubois Declercq0Roxane Pouliot1Centre LOEX de l'Université Laval, Génie Tissulaire et Régénération, LOEX-Centre de Recherche FRSQ du CHU, Aile-R, 1401 18e rue, Québec, QC, G1J 1Z4, CanadaCentre LOEX de l'Université Laval, Génie Tissulaire et Régénération, LOEX-Centre de Recherche FRSQ du CHU, Aile-R, 1401 18e rue, Québec, QC, G1J 1Z4, CanadaPsoriasis is a chronic, proliferative, and inflammatory skin disease affecting 2-3% of the population and is characterized by red plaques with white scales. Psoriasis is a disease that can affect many aspects of professional and social life. Currently, several treatments are available to help control psoriasis such as methotrexate, ciclosporin, and oral retinoids. However, the available treatments are only able to relieve the symptoms and lives of individuals. The discovery of new immunological factors and a better understanding of psoriasis have turned to the use of immunological pathways and could develop new biological drugs against specific immunological elements that cause psoriasis. Biological drugs are less toxic to the body and more effective than traditional therapies. Thus, they should improve the quality of life of patients with psoriasis. This review describes new psoriasis treatments, which are on the market or currently in clinical trials that are being used to treat moderate-to-severe plaque psoriasis. In addition, this paper describes the characteristics and mechanisms in detail. In general, biological drugs are well tolerated and appear to be an effective alternative to conventional therapies. However, their effectiveness and long-term side effects need to be further researched.http://dx.doi.org/10.1155/2013/980419
spellingShingle Sarah Dubois Declercq
Roxane Pouliot
Promising New Treatments for Psoriasis
The Scientific World Journal
title Promising New Treatments for Psoriasis
title_full Promising New Treatments for Psoriasis
title_fullStr Promising New Treatments for Psoriasis
title_full_unstemmed Promising New Treatments for Psoriasis
title_short Promising New Treatments for Psoriasis
title_sort promising new treatments for psoriasis
url http://dx.doi.org/10.1155/2013/980419
work_keys_str_mv AT sarahduboisdeclercq promisingnewtreatmentsforpsoriasis
AT roxanepouliot promisingnewtreatmentsforpsoriasis