Buruli Ulcer: Treatment Challenges at Three Centres in Ghana

Aims. This retrospective study was to identify some challenges in the treatment of Buruli ulcer (BU) and present a proposed treatment regime. Materials and Methods. Information from patients medical records, hospital database, and follow-up findings on BU treatment procedures from 1994 to 1998 and...

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Main Authors: Pius Agbenorku, Isaac K. Donwi, Pawson Kuadzi, Paul Saunderson
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Tropical Medicine
Online Access:http://dx.doi.org/10.1155/2012/371915
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author Pius Agbenorku
Isaac K. Donwi
Pawson Kuadzi
Paul Saunderson
author_facet Pius Agbenorku
Isaac K. Donwi
Pawson Kuadzi
Paul Saunderson
author_sort Pius Agbenorku
collection DOAJ
description Aims. This retrospective study was to identify some challenges in the treatment of Buruli ulcer (BU) and present a proposed treatment regime. Materials and Methods. Information from patients medical records, hospital database, and follow-up findings on BU treatment procedures from 1994 to 1998 and from 2004 to 2007 at three research sites in Ghana were reviewed to determine the treatment challenges encountered. Data needed were recorded and analyzed, and results presented using SPSS version 17.0. Results. A total of 489 BU patients information was selected for the study. A majority (56.90%, ) of the patients were children (0–14 years), with a mean age of 12.8 years. Significant challenges in BU treatment in Ghana identified included sequelae ( ), delayed treatment ( ), and high treatment cost ( ). Duration of hospital stay was clearly correlated with the time spent at home prior to admission; spearman’s rank correlation coefficient was 0.72 (95% CI 0.42–0.87). Conclusion. Delays in seeking treatment among BU patients were the main factor which resulted in most of the other factors contributing to the challenges in treatment. A combination of psychosocial and biomedical approach was proposed as holistic method to alleviate the challenges in BU treatment.
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publishDate 2012-01-01
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series Journal of Tropical Medicine
spelling doaj-art-3c0c02824c2d4ff088261e6072d49fa82025-08-20T02:08:19ZengWileyJournal of Tropical Medicine1687-96861687-96942012-01-01201210.1155/2012/371915371915Buruli Ulcer: Treatment Challenges at Three Centres in GhanaPius Agbenorku0Isaac K. Donwi1Pawson Kuadzi2Paul Saunderson3Reconstructive Plastic Surgery and Burns Unit, Komfo Anokye Teaching Hospital School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, GhanaDepartment of Mathematics, College of Science, Kwame Nkrumah University of Science and Technology, Kumasi, GhanaDepartment of Mathematics, College of Science, Kwame Nkrumah University of Science and Technology, Kumasi, GhanaAmerican Leprosy Missions, 1 Alm Way, Greenville, SC 29601, USAAims. This retrospective study was to identify some challenges in the treatment of Buruli ulcer (BU) and present a proposed treatment regime. Materials and Methods. Information from patients medical records, hospital database, and follow-up findings on BU treatment procedures from 1994 to 1998 and from 2004 to 2007 at three research sites in Ghana were reviewed to determine the treatment challenges encountered. Data needed were recorded and analyzed, and results presented using SPSS version 17.0. Results. A total of 489 BU patients information was selected for the study. A majority (56.90%, ) of the patients were children (0–14 years), with a mean age of 12.8 years. Significant challenges in BU treatment in Ghana identified included sequelae ( ), delayed treatment ( ), and high treatment cost ( ). Duration of hospital stay was clearly correlated with the time spent at home prior to admission; spearman’s rank correlation coefficient was 0.72 (95% CI 0.42–0.87). Conclusion. Delays in seeking treatment among BU patients were the main factor which resulted in most of the other factors contributing to the challenges in treatment. A combination of psychosocial and biomedical approach was proposed as holistic method to alleviate the challenges in BU treatment.http://dx.doi.org/10.1155/2012/371915
spellingShingle Pius Agbenorku
Isaac K. Donwi
Pawson Kuadzi
Paul Saunderson
Buruli Ulcer: Treatment Challenges at Three Centres in Ghana
Journal of Tropical Medicine
title Buruli Ulcer: Treatment Challenges at Three Centres in Ghana
title_full Buruli Ulcer: Treatment Challenges at Three Centres in Ghana
title_fullStr Buruli Ulcer: Treatment Challenges at Three Centres in Ghana
title_full_unstemmed Buruli Ulcer: Treatment Challenges at Three Centres in Ghana
title_short Buruli Ulcer: Treatment Challenges at Three Centres in Ghana
title_sort buruli ulcer treatment challenges at three centres in ghana
url http://dx.doi.org/10.1155/2012/371915
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AT isaackdonwi buruliulcertreatmentchallengesatthreecentresinghana
AT pawsonkuadzi buruliulcertreatmentchallengesatthreecentresinghana
AT paulsaunderson buruliulcertreatmentchallengesatthreecentresinghana