M1 macrophage inhibits ferroptosis in Pseudomonas aeruginosa-induced kidney epithelial cell injury through the iNOS/ NO pathway without thiol

M1 macrophage inhibits ferroptosis in Pseudomonas aeruginosa-induced kidney epithelial cell injury through the iNOS/ NO pathway without thiol

InstructionPseudomonas aeruginosa (PA) is one of the common pathogens of urinary tract infection. It can lead to urosepsis and renal damage. However, the mechanism by which P. aeruginosa affects epithelial cells is not clear.MethodsHK2 cells were treated with extracted PA supernatant (PA.sup). Diffe...

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Bibliographic Details
Main Authors: Peixiang Lu, Xiaojie Bai, Linfa Guo, Kuerban Tuoheti, Shanzhi Zhan, Tongzu Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
macrophage
Pseudomonas aeruginosa
epithelial cells
kidney
ferroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1597160/full
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