Feature Selection Algorithms Combined with Experimental Validation Reveal COL10A1 and TMPRSS4 Genes as Potential Diagnostic Biomarkers in Pancreatic Ductal Adenocarcinoma

Feature Selection Algorithms Combined with Experimental Validation Reveal COL10A1 and TMPRSS4 Genes as Potential Diagnostic Biomarkers in Pancreatic Ductal Adenocarcinoma

Background: Pancreatic adenocarcinoma (PAAD) is often diagnosed at a late stage, preventing curative surgery. Early detection is crucial for improving patient outcomes. This study aims to discover potential biomarkers for identifying asymptomatic PAAD tumors.Method: In this case-control study, two g...

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Bibliographic Details
Main Authors: Neda Shajari, Amin Ramezani, Ahmad Tahmasebi, Mohammad Hossein Anbardar, Zahra Roshanizadeh, Abbas Ghaderi
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2025-07-01
Series:Middle East Journal of Cancer
Subjects:
pancreatic neoplasms
gene expression profiling
biomarkers
diagnosis
Online Access:https://mejc.sums.ac.ir/article_50538_fbb10ccab6a2cdbe427cc58334b43e6f.pdf
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