Advancements and global perspectives in the green synthesis of silver nanoparticles: A two-decade analysis
Silver nanoparticles, also known as AgNPs, have earned significant attention from scientists due to their remarkable physicochemical characteristics. These traits encompass potent antibacterial effects, plasmonic activity, and a notable surface area-to-volume ratio. The conventional methods for synt...
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| Format: | Article |
| Language: | English |
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Pensoft Publishers
2025-02-01
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| Series: | Pharmacia |
| Online Access: | https://pharmacia.pensoft.net/article/142156/download/pdf/ |
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| author | Islam Hamad Shereen M. Aleidi Walhan Alshaer Shrouq Twal Mona Al Olabi Yasser Bustanji |
| author_facet | Islam Hamad Shereen M. Aleidi Walhan Alshaer Shrouq Twal Mona Al Olabi Yasser Bustanji |
| author_sort | Islam Hamad |
| collection | DOAJ |
| description | Silver nanoparticles, also known as AgNPs, have earned significant attention from scientists due to their remarkable physicochemical characteristics. These traits encompass potent antibacterial effects, plasmonic activity, and a notable surface area-to-volume ratio. The conventional methods for synthesizing (AgNPs) typically involve the use of hazardous chemicals. This practice not only poses risks to the environment and human health but also goes against the core principles of sustainability that underpin modern scientific research. This has led to the concept of “green synthesis,” which pertains to the utilization of natural resources, including plant extracts, microbes, and biomolecules, with the intent of filling the role of stabilizing and reducing agents. Bibliometric research analyzes systematic literary data statistically. This study used bibliometric indicators to examine, map, and evaluate global green synthesis research output on AgNPs. A Scopus search was performed to find all English-language peer-reviewed scientific works on AgNPs produced in the last two decades. Bibliometric indicators were determined using VOSviewer and Biblioshiny. We made thematic, conceptual, and visualization charts. A grand total of 4079 published documents were obtained. Indian authors exhibited the highest level of activity, accounting for around 41.8% of the overall publications. Conversely, researchers from the United States (USA) demonstrated the most substantial scientific influence. The findings of the study indicate a lack of substantial international collaboration within the scope of this research domain. The process of keyword mapping has successfully identified the primary areas of research focus and current trends within this particular field of study. The key clusters identified through theme and hotspot analyses included multimodal techniques in biosynthesis and characterization, antibacterial and antifungal action, in addition to anticancer, antioxidant activity, and apoptosis. The present work undertook an analysis and mapping of the growing domain of green synthesis research of (AgNPs), while also identifying diverse applications associated with AgNPs. AgNPs were employed as drug delivery systems in order to selectively target cancer cells and enhance the bioavailability of anticancer drugs. The study demonstrated the potential of customizing these NPs for precise medication administration by including biocompatible chemicals through biofunctionalization. Moreover, AgNPs have been applied in diagnostic imaging due to their good optical characteristics. However, clinical research is still required in order to transform this fundamental insight into formulations that are clinically useful. |
| format | Article |
| id | doaj-art-3c014aaaf5f748cbb9ac02a387ea6eaf |
| institution | OA Journals |
| issn | 2603-557X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Pensoft Publishers |
| record_format | Article |
| series | Pharmacia |
| spelling | doaj-art-3c014aaaf5f748cbb9ac02a387ea6eaf2025-08-20T02:12:57ZengPensoft PublishersPharmacia2603-557X2025-02-017211310.3897/pharmacia.72.e142156142156Advancements and global perspectives in the green synthesis of silver nanoparticles: A two-decade analysisIslam Hamad0Shereen M. Aleidi1Walhan Alshaer2Shrouq Twal3Mona Al Olabi4Yasser Bustanji5American University of MadabaThe University of JordanThe University of JordanAmerican University of MadabaUniversity of PetraUniversity of SharjahSilver nanoparticles, also known as AgNPs, have earned significant attention from scientists due to their remarkable physicochemical characteristics. These traits encompass potent antibacterial effects, plasmonic activity, and a notable surface area-to-volume ratio. The conventional methods for synthesizing (AgNPs) typically involve the use of hazardous chemicals. This practice not only poses risks to the environment and human health but also goes against the core principles of sustainability that underpin modern scientific research. This has led to the concept of “green synthesis,” which pertains to the utilization of natural resources, including plant extracts, microbes, and biomolecules, with the intent of filling the role of stabilizing and reducing agents. Bibliometric research analyzes systematic literary data statistically. This study used bibliometric indicators to examine, map, and evaluate global green synthesis research output on AgNPs. A Scopus search was performed to find all English-language peer-reviewed scientific works on AgNPs produced in the last two decades. Bibliometric indicators were determined using VOSviewer and Biblioshiny. We made thematic, conceptual, and visualization charts. A grand total of 4079 published documents were obtained. Indian authors exhibited the highest level of activity, accounting for around 41.8% of the overall publications. Conversely, researchers from the United States (USA) demonstrated the most substantial scientific influence. The findings of the study indicate a lack of substantial international collaboration within the scope of this research domain. The process of keyword mapping has successfully identified the primary areas of research focus and current trends within this particular field of study. The key clusters identified through theme and hotspot analyses included multimodal techniques in biosynthesis and characterization, antibacterial and antifungal action, in addition to anticancer, antioxidant activity, and apoptosis. The present work undertook an analysis and mapping of the growing domain of green synthesis research of (AgNPs), while also identifying diverse applications associated with AgNPs. AgNPs were employed as drug delivery systems in order to selectively target cancer cells and enhance the bioavailability of anticancer drugs. The study demonstrated the potential of customizing these NPs for precise medication administration by including biocompatible chemicals through biofunctionalization. Moreover, AgNPs have been applied in diagnostic imaging due to their good optical characteristics. However, clinical research is still required in order to transform this fundamental insight into formulations that are clinically useful.https://pharmacia.pensoft.net/article/142156/download/pdf/ |
| spellingShingle | Islam Hamad Shereen M. Aleidi Walhan Alshaer Shrouq Twal Mona Al Olabi Yasser Bustanji Advancements and global perspectives in the green synthesis of silver nanoparticles: A two-decade analysis Pharmacia |
| title | Advancements and global perspectives in the green synthesis of silver nanoparticles: A two-decade analysis |
| title_full | Advancements and global perspectives in the green synthesis of silver nanoparticles: A two-decade analysis |
| title_fullStr | Advancements and global perspectives in the green synthesis of silver nanoparticles: A two-decade analysis |
| title_full_unstemmed | Advancements and global perspectives in the green synthesis of silver nanoparticles: A two-decade analysis |
| title_short | Advancements and global perspectives in the green synthesis of silver nanoparticles: A two-decade analysis |
| title_sort | advancements and global perspectives in the green synthesis of silver nanoparticles a two decade analysis |
| url | https://pharmacia.pensoft.net/article/142156/download/pdf/ |
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