Focal Area of Low T2 Signal on MRI Scans in a Heterogeneous Uterine Leiomyoma Does Not Exclude the Possibility of Malignancy: A Report of Two Cases
Conclusion: MRI is crucial for distinguishing leiomyomas from sarcomas. We propose combining T2WI and DWI with ADC for this purpose, noting limitations in each sequence’s reliability. Suggestive MRI criteria for malignancy in sarcomas are identified, emphasizing the need for comprehensive imaging an...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Case Reports in Radiology |
| Online Access: | http://dx.doi.org/10.1155/crra/5388015 |
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| author | Siegfried Hélage Claudia Laponche Margaux Homps Jean-Noël Buy Pierre-Alexandre Just Denis Jacob Michel Ghossain Élisabeth Dion |
| author_facet | Siegfried Hélage Claudia Laponche Margaux Homps Jean-Noël Buy Pierre-Alexandre Just Denis Jacob Michel Ghossain Élisabeth Dion |
| author_sort | Siegfried Hélage |
| collection | DOAJ |
| description | Conclusion: MRI is crucial for distinguishing leiomyomas from sarcomas. We propose combining T2WI and DWI with ADC for this purpose, noting limitations in each sequence’s reliability. Suggestive MRI criteria for malignancy in sarcomas are identified, emphasizing the need for comprehensive imaging analysis. In characterizing uterine smooth muscle tumors, particularly when analyzing leiomyoma variants, DWI emerges as the dominant sequence, with T2WI serving as a secondary sequence. ADC values aid in histopathological hypothesis, but caution is warranted due to overlap with benign lesions. This approach may refine preoperative diagnosis and guide therapeutic management. |
| format | Article |
| id | doaj-art-3bf6e4c759fe48e29494ab70e7d22fcc |
| institution | OA Journals |
| issn | 2090-6870 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Radiology |
| spelling | doaj-art-3bf6e4c759fe48e29494ab70e7d22fcc2025-08-20T02:12:49ZengWileyCase Reports in Radiology2090-68702025-01-01202510.1155/crra/5388015Focal Area of Low T2 Signal on MRI Scans in a Heterogeneous Uterine Leiomyoma Does Not Exclude the Possibility of Malignancy: A Report of Two CasesSiegfried Hélage0Claudia Laponche1Margaux Homps2Jean-Noël Buy3Pierre-Alexandre Just4Denis Jacob5Michel Ghossain6Élisabeth Dion7Department of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of RadiologyDepartment of PathologyDepartment of Gynecological SurgeryDepartment of RadiologyDepartment of RadiologyConclusion: MRI is crucial for distinguishing leiomyomas from sarcomas. We propose combining T2WI and DWI with ADC for this purpose, noting limitations in each sequence’s reliability. Suggestive MRI criteria for malignancy in sarcomas are identified, emphasizing the need for comprehensive imaging analysis. In characterizing uterine smooth muscle tumors, particularly when analyzing leiomyoma variants, DWI emerges as the dominant sequence, with T2WI serving as a secondary sequence. ADC values aid in histopathological hypothesis, but caution is warranted due to overlap with benign lesions. This approach may refine preoperative diagnosis and guide therapeutic management.http://dx.doi.org/10.1155/crra/5388015 |
| spellingShingle | Siegfried Hélage Claudia Laponche Margaux Homps Jean-Noël Buy Pierre-Alexandre Just Denis Jacob Michel Ghossain Élisabeth Dion Focal Area of Low T2 Signal on MRI Scans in a Heterogeneous Uterine Leiomyoma Does Not Exclude the Possibility of Malignancy: A Report of Two Cases Case Reports in Radiology |
| title | Focal Area of Low T2 Signal on MRI Scans in a Heterogeneous Uterine Leiomyoma Does Not Exclude the Possibility of Malignancy: A Report of Two Cases |
| title_full | Focal Area of Low T2 Signal on MRI Scans in a Heterogeneous Uterine Leiomyoma Does Not Exclude the Possibility of Malignancy: A Report of Two Cases |
| title_fullStr | Focal Area of Low T2 Signal on MRI Scans in a Heterogeneous Uterine Leiomyoma Does Not Exclude the Possibility of Malignancy: A Report of Two Cases |
| title_full_unstemmed | Focal Area of Low T2 Signal on MRI Scans in a Heterogeneous Uterine Leiomyoma Does Not Exclude the Possibility of Malignancy: A Report of Two Cases |
| title_short | Focal Area of Low T2 Signal on MRI Scans in a Heterogeneous Uterine Leiomyoma Does Not Exclude the Possibility of Malignancy: A Report of Two Cases |
| title_sort | focal area of low t2 signal on mri scans in a heterogeneous uterine leiomyoma does not exclude the possibility of malignancy a report of two cases |
| url | http://dx.doi.org/10.1155/crra/5388015 |
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