Focal Area of Low T2 Signal on MRI Scans in a Heterogeneous Uterine Leiomyoma Does Not Exclude the Possibility of Malignancy: A Report of Two Cases

Conclusion: MRI is crucial for distinguishing leiomyomas from sarcomas. We propose combining T2WI and DWI with ADC for this purpose, noting limitations in each sequence’s reliability. Suggestive MRI criteria for malignancy in sarcomas are identified, emphasizing the need for comprehensive imaging an...

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Bibliographic Details
Main Authors: Siegfried Hélage, Claudia Laponche, Margaux Homps, Jean-Noël Buy, Pierre-Alexandre Just, Denis Jacob, Michel Ghossain, Élisabeth Dion
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Case Reports in Radiology
Online Access:http://dx.doi.org/10.1155/crra/5388015
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Summary:Conclusion: MRI is crucial for distinguishing leiomyomas from sarcomas. We propose combining T2WI and DWI with ADC for this purpose, noting limitations in each sequence’s reliability. Suggestive MRI criteria for malignancy in sarcomas are identified, emphasizing the need for comprehensive imaging analysis. In characterizing uterine smooth muscle tumors, particularly when analyzing leiomyoma variants, DWI emerges as the dominant sequence, with T2WI serving as a secondary sequence. ADC values aid in histopathological hypothesis, but caution is warranted due to overlap with benign lesions. This approach may refine preoperative diagnosis and guide therapeutic management.
ISSN:2090-6870