Diurnal Asymmetric Loading Modulates Cell Phenotype in Intervertebral Disc

Diurnal Asymmetric Loading Modulates Cell Phenotype in Intervertebral Disc

ABSTRACT Purpose This study tested the hypothesis that asymmetric dynamic loading alone or in combination with static loading influences the morphological and biological characteristics of the intervertebral disc (IVD) cells in an ex vivo model. Methods Bovine caudal IVDs were assigned to four group...

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Bibliographic Details
Main Authors: Ying Zhang, Jianbiao Xu, Zhiyu Zhou, R. Geoff Richards, Mauro Alini, Sibylle Grad, Zhen Li
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:JOR Spine
Subjects:
asymmetric loading
disc degeneration
intervertebral disc
organ culture model
scoliosis
Online Access:https://doi.org/10.1002/jsp2.70068
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