Pre-clinical markers for diagnosis of diabetic nephropathy in patients with type 1 diabetes mellitus

Due to progressive nature of diabetic nephropathy (DN) and limited effectiveness of therapeutic efforts at clinically overt stages, diagnosisof pre-clinical (and, therefore, potentially reversible) DN is especially important. To date, however, test for microalbuminuriaremains the only technique appl...

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Main Authors: Nadezhda Olegovna Lebedeva, Olga Konstantinovna Vikulova
Format: Article
Language:English
Published: Endocrinology Research Centre 2012-06-01
Series:Сахарный диабет
Subjects:
Online Access:https://www.dia-endojournals.ru/jour/article/view/5517
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author Nadezhda Olegovna Lebedeva
Olga Konstantinovna Vikulova
author_facet Nadezhda Olegovna Lebedeva
Olga Konstantinovna Vikulova
author_sort Nadezhda Olegovna Lebedeva
collection DOAJ
description Due to progressive nature of diabetic nephropathy (DN) and limited effectiveness of therapeutic efforts at clinically overt stages, diagnosisof pre-clinical (and, therefore, potentially reversible) DN is especially important. To date, however, test for microalbuminuriaremains the only technique applicable for early diagnostics of DN. Current review addresses search for potential markers of pre-clinical stage of DN in patients with type 1 diabetes mellitus and embracesdata from latest experimental and clinical studies in this area.
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spelling doaj-art-3bf3572192ad4c81895f8fdbde1a086e2025-08-20T02:29:34ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782012-06-01152384510.14341/2072-0351-55175475Pre-clinical markers for diagnosis of diabetic nephropathy in patients with type 1 diabetes mellitusNadezhda Olegovna Lebedeva0Olga Konstantinovna Vikulova1Endocrinology Research Centre, MoscowEndocrinology Research Centre, MoscowDue to progressive nature of diabetic nephropathy (DN) and limited effectiveness of therapeutic efforts at clinically overt stages, diagnosisof pre-clinical (and, therefore, potentially reversible) DN is especially important. To date, however, test for microalbuminuriaremains the only technique applicable for early diagnostics of DN. Current review addresses search for potential markers of pre-clinical stage of DN in patients with type 1 diabetes mellitus and embracesdata from latest experimental and clinical studies in this area.https://www.dia-endojournals.ru/jour/article/view/5517diabetic nephropathydiabetes mellitus type 1pre-clinical diagnosticsproteomic analysis
spellingShingle Nadezhda Olegovna Lebedeva
Olga Konstantinovna Vikulova
Pre-clinical markers for diagnosis of diabetic nephropathy in patients with type 1 diabetes mellitus
Сахарный диабет
diabetic nephropathy
diabetes mellitus type 1
pre-clinical diagnostics
proteomic analysis
title Pre-clinical markers for diagnosis of diabetic nephropathy in patients with type 1 diabetes mellitus
title_full Pre-clinical markers for diagnosis of diabetic nephropathy in patients with type 1 diabetes mellitus
title_fullStr Pre-clinical markers for diagnosis of diabetic nephropathy in patients with type 1 diabetes mellitus
title_full_unstemmed Pre-clinical markers for diagnosis of diabetic nephropathy in patients with type 1 diabetes mellitus
title_short Pre-clinical markers for diagnosis of diabetic nephropathy in patients with type 1 diabetes mellitus
title_sort pre clinical markers for diagnosis of diabetic nephropathy in patients with type 1 diabetes mellitus
topic diabetic nephropathy
diabetes mellitus type 1
pre-clinical diagnostics
proteomic analysis
url https://www.dia-endojournals.ru/jour/article/view/5517
work_keys_str_mv AT nadezhdaolegovnalebedeva preclinicalmarkersfordiagnosisofdiabeticnephropathyinpatientswithtype1diabetesmellitus
AT olgakonstantinovnavikulova preclinicalmarkersfordiagnosisofdiabeticnephropathyinpatientswithtype1diabetesmellitus