Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking
Corneal cross-linking (CXL) is increasingly performed in ophthalmology with high success rates for progressive keratoconus and other types of ectasia. Despite being an established procedure, some molecular and clinical aspects still require additional studies. This review presents a critical analysi...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2014/890823 |
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| author | Amanda C. da Paz Patrícia A. Bersanetti Marcella Q. Salomão Renato Ambrósio Paulo Schor |
| author_facet | Amanda C. da Paz Patrícia A. Bersanetti Marcella Q. Salomão Renato Ambrósio Paulo Schor |
| author_sort | Amanda C. da Paz |
| collection | DOAJ |
| description | Corneal cross-linking (CXL) is increasingly performed in ophthalmology with high success rates for progressive keratoconus and other types of ectasia. Despite being an established procedure, some molecular and clinical aspects still require additional studies. This review presents a critical analysis of some established topics and others that are still controversial. In addition, this review examines new technologies and techniques (transepithelial and ultrafast CXL), uses of corneal CXL including natural products and biomolecules as CXL promoters, and evidence for in vitro and in vivo indirect effectiveness. |
| format | Article |
| id | doaj-art-3beec273f1b843b7b87dfe9a898fc2e7 |
| institution | OA Journals |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-3beec273f1b843b7b87dfe9a898fc2e72025-08-20T02:16:33ZengWileyJournal of Ophthalmology2090-004X2090-00582014-01-01201410.1155/2014/890823890823Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-LinkingAmanda C. da Paz0Patrícia A. Bersanetti1Marcella Q. Salomão2Renato Ambrósio3Paulo Schor4Department of Ophthalmology and Visual Sciences, Paulista School of Medicine, Federal University of São Paulo (UNIFESP), São Paulo, SP, BrazilDepartment of Ophthalmology and Visual Sciences, Paulista School of Medicine, Federal University of São Paulo (UNIFESP), São Paulo, SP, BrazilInstituto de Olhos Renato Ambrósio, 20520-050 Rio de Janeiro, RJ, BrazilDepartment of Ophthalmology and Visual Sciences, Paulista School of Medicine, Federal University of São Paulo (UNIFESP), São Paulo, SP, BrazilDepartment of Ophthalmology and Visual Sciences, Paulista School of Medicine, Federal University of São Paulo (UNIFESP), São Paulo, SP, BrazilCorneal cross-linking (CXL) is increasingly performed in ophthalmology with high success rates for progressive keratoconus and other types of ectasia. Despite being an established procedure, some molecular and clinical aspects still require additional studies. This review presents a critical analysis of some established topics and others that are still controversial. In addition, this review examines new technologies and techniques (transepithelial and ultrafast CXL), uses of corneal CXL including natural products and biomolecules as CXL promoters, and evidence for in vitro and in vivo indirect effectiveness.http://dx.doi.org/10.1155/2014/890823 |
| spellingShingle | Amanda C. da Paz Patrícia A. Bersanetti Marcella Q. Salomão Renato Ambrósio Paulo Schor Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking Journal of Ophthalmology |
| title | Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking |
| title_full | Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking |
| title_fullStr | Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking |
| title_full_unstemmed | Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking |
| title_short | Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking |
| title_sort | theoretical basis laboratory evidence and clinical research of chemical surgery of the cornea cross linking |
| url | http://dx.doi.org/10.1155/2014/890823 |
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