β-catenin-α-catenin and actomyosin signaling differentially regulate growth cone contours and axon undulation and branching of retinal ganglion cells in situ

β-catenin-α-catenin and actomyosin signaling differentially regulate growth cone contours and axon undulation and branching of retinal ganglion cells in situ

IntroductionCadherin adhesive and actomyosin signaling are key cytomechanical cues required for neuronal circuit formation, but whether they function together to sculpt developing neurons is not known. Previously, we demonstrated that a β-catenin mutant (β-catNTERM) that disrupts binding of endogeno...

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Bibliographic Details
Main Authors: Valerie Lew, Sukaynah Khetani, Simran Kaur, William Woodward, Sukmin Sandhu, Radhika Rawat, Tamira Elul
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
growth cone
adhesion
cytoskeleton
axon
Xenopus
retinal ganglion cells
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2025.1572298/full
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