One health approach based descriptive study on Coxiella burnetii infections in camels and abattoir workers in the United Arab Emirates

Abstract Coxiellosis is a zoonotic bacterial disease caused by Coxiella burnetii (C. burnetii) infection that occurs as subclinical and clinical infections in animals and humans worldwide except in the Antarctica and New Zealand. The objectives of this study were to estimate the seroprevalences of C...

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Main Authors: Mohamud Sheek-Hussein, Aboma Zewude, Aminu S. Abdullahi, Nabeeha Hassan Abdelgaleel, Hassan Zackaria Ali Ishag, Mohd Farouk Yusof, Mohammed Saleh ALBreiki, Asma Mohamed Abdi Shah, Jamila AlNeyadi, Babiker Osman, Amir Abdullah Hassen, Mervat Mari Al Nuaimat, Kaltham Kayaf, Mohamed Elfatih Hamad, Ahmed R Alsuwaidi, Balázs Ádám, Robert Barigye, Gobena Ameni
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-97167-0
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author Mohamud Sheek-Hussein
Aboma Zewude
Aminu S. Abdullahi
Nabeeha Hassan Abdelgaleel
Hassan Zackaria Ali Ishag
Mohd Farouk Yusof
Mohammed Saleh ALBreiki
Asma Mohamed Abdi Shah
Jamila AlNeyadi
Babiker Osman
Amir Abdullah Hassen
Mervat Mari Al Nuaimat
Kaltham Kayaf
Mohamed Elfatih Hamad
Ahmed R Alsuwaidi
Balázs Ádám
Robert Barigye
Gobena Ameni
author_facet Mohamud Sheek-Hussein
Aboma Zewude
Aminu S. Abdullahi
Nabeeha Hassan Abdelgaleel
Hassan Zackaria Ali Ishag
Mohd Farouk Yusof
Mohammed Saleh ALBreiki
Asma Mohamed Abdi Shah
Jamila AlNeyadi
Babiker Osman
Amir Abdullah Hassen
Mervat Mari Al Nuaimat
Kaltham Kayaf
Mohamed Elfatih Hamad
Ahmed R Alsuwaidi
Balázs Ádám
Robert Barigye
Gobena Ameni
author_sort Mohamud Sheek-Hussein
collection DOAJ
description Abstract Coxiellosis is a zoonotic bacterial disease caused by Coxiella burnetii (C. burnetii) infection that occurs as subclinical and clinical infections in animals and humans worldwide except in the Antarctica and New Zealand. The objectives of this study were to estimate the seroprevalences of C. burnetti infections in slaughtered camels and abattoir workers as well as to detect C. burnetii DNA in the clotted blood in the same study subjects at Al Bawadi abattoir of Al Ain city, in the United Arab Emirates, UAE. A cross-sectional study design was used to test 393 slaughtered camels and 86 abattoir workers for C. burnetii antibodies between March 2022 and July 2023 using enzyme-linked immunosorbent assay (ELISA) kits supplied by ID Vet multispecies and Abbexa, respectively. Besides, real-time polymerase chain reaction (qPCR) was used for the detection of C. burnetti DNA in clotted blood of 366 camels and 86 abattoir workers. The seroprevalences of C. burnetii infection were 52.9% (95% confidence interval, CI: 46.0, 60.6%) and 24.4% (95% CI: 15.1, 37.3%) in camels and abattoir workers. But, C. burnetii DNA was not detected in clotted blood samples of camels and abattoir workers. Sex, age and body condition of the camels were not associated with the seroprevalence of C. burnetii while abattoir workers of African origin were more likely to be seropositive (odds ratio, OR = 3.70; 95% CI: 1.05, 13.60) than abattoir workers of south Asian origin. The seroprevalences of C. burnetii infections were high in both slaughtered camels and abattoir workers although its DNA was not detected in the clotted blood of either of the study subjects.
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spelling doaj-art-3bed691627bb47278dd0c8d44a4b8efd2025-08-20T03:06:57ZengNature PortfolioScientific Reports2045-23222025-04-0115111210.1038/s41598-025-97167-0One health approach based descriptive study on Coxiella burnetii infections in camels and abattoir workers in the United Arab EmiratesMohamud Sheek-Hussein0Aboma Zewude1Aminu S. Abdullahi2Nabeeha Hassan Abdelgaleel3Hassan Zackaria Ali Ishag4Mohd Farouk Yusof5Mohammed Saleh ALBreiki6Asma Mohamed Abdi Shah7Jamila AlNeyadi8Babiker Osman9Amir Abdullah Hassen10Mervat Mari Al Nuaimat11Kaltham Kayaf12Mohamed Elfatih Hamad13Ahmed R Alsuwaidi14Balázs Ádám15Robert Barigye16Gobena Ameni17Institute of Public Health, College of Medicine and Health Sciences, United Arab Emirates UniversityDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates UniversityInstitute of Public Health, College of Medicine and Health Sciences, United Arab Emirates UniversityDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates UniversityBiosecurity Affairs Division, Development and Innovation Sector, Abu Dhabi Agriculture and Food Safety AuthorityBiosecurity Affairs Division, Development and Innovation Sector, Abu Dhabi Agriculture and Food Safety AuthorityBiosecurity Affairs Division, Development and Innovation Sector, Abu Dhabi Agriculture and Food Safety AuthorityBiosecurity Affairs Division, Development and Innovation Sector, Abu Dhabi Agriculture and Food Safety AuthorityAl Ain MunicipalityAl Ain MunicipalityAl Ain MunicipalityAnimal Development & Health Department, Ministry of Climate Change & EnvironmentAnimal Development & Health Department, Ministry of Climate Change & EnvironmentDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates UniversityDepartment of Pediatrics, College of Medicine and Health Sciences, United Arab Emirates UniversityInstitute of Public Health, College of Medicine and Health Sciences, United Arab Emirates UniversityDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates UniversityDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates UniversityAbstract Coxiellosis is a zoonotic bacterial disease caused by Coxiella burnetii (C. burnetii) infection that occurs as subclinical and clinical infections in animals and humans worldwide except in the Antarctica and New Zealand. The objectives of this study were to estimate the seroprevalences of C. burnetti infections in slaughtered camels and abattoir workers as well as to detect C. burnetii DNA in the clotted blood in the same study subjects at Al Bawadi abattoir of Al Ain city, in the United Arab Emirates, UAE. A cross-sectional study design was used to test 393 slaughtered camels and 86 abattoir workers for C. burnetii antibodies between March 2022 and July 2023 using enzyme-linked immunosorbent assay (ELISA) kits supplied by ID Vet multispecies and Abbexa, respectively. Besides, real-time polymerase chain reaction (qPCR) was used for the detection of C. burnetti DNA in clotted blood of 366 camels and 86 abattoir workers. The seroprevalences of C. burnetii infection were 52.9% (95% confidence interval, CI: 46.0, 60.6%) and 24.4% (95% CI: 15.1, 37.3%) in camels and abattoir workers. But, C. burnetii DNA was not detected in clotted blood samples of camels and abattoir workers. Sex, age and body condition of the camels were not associated with the seroprevalence of C. burnetii while abattoir workers of African origin were more likely to be seropositive (odds ratio, OR = 3.70; 95% CI: 1.05, 13.60) than abattoir workers of south Asian origin. The seroprevalences of C. burnetii infections were high in both slaughtered camels and abattoir workers although its DNA was not detected in the clotted blood of either of the study subjects.https://doi.org/10.1038/s41598-025-97167-0Abattoir workersCoxiella burnetii infectionDromedary camelsQ feverSeroprevalenceUnited Arab Emirates
spellingShingle Mohamud Sheek-Hussein
Aboma Zewude
Aminu S. Abdullahi
Nabeeha Hassan Abdelgaleel
Hassan Zackaria Ali Ishag
Mohd Farouk Yusof
Mohammed Saleh ALBreiki
Asma Mohamed Abdi Shah
Jamila AlNeyadi
Babiker Osman
Amir Abdullah Hassen
Mervat Mari Al Nuaimat
Kaltham Kayaf
Mohamed Elfatih Hamad
Ahmed R Alsuwaidi
Balázs Ádám
Robert Barigye
Gobena Ameni
One health approach based descriptive study on Coxiella burnetii infections in camels and abattoir workers in the United Arab Emirates
Scientific Reports
Abattoir workers
Coxiella burnetii infection
Dromedary camels
Q fever
Seroprevalence
United Arab Emirates
title One health approach based descriptive study on Coxiella burnetii infections in camels and abattoir workers in the United Arab Emirates
title_full One health approach based descriptive study on Coxiella burnetii infections in camels and abattoir workers in the United Arab Emirates
title_fullStr One health approach based descriptive study on Coxiella burnetii infections in camels and abattoir workers in the United Arab Emirates
title_full_unstemmed One health approach based descriptive study on Coxiella burnetii infections in camels and abattoir workers in the United Arab Emirates
title_short One health approach based descriptive study on Coxiella burnetii infections in camels and abattoir workers in the United Arab Emirates
title_sort one health approach based descriptive study on coxiella burnetii infections in camels and abattoir workers in the united arab emirates
topic Abattoir workers
Coxiella burnetii infection
Dromedary camels
Q fever
Seroprevalence
United Arab Emirates
url https://doi.org/10.1038/s41598-025-97167-0
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