Cardiometabolic deaths in black and white men: Tracing the risks from early- to mid-adulthood

Objective: This study aimed to estimate and compare cardiometabolic disease (CMD) mortality in U.S. Black and White men during the transition from early adulthood to middle age. Methods: Using 2022 National Vital Statistics System data and standard period life table methods, we estimated the risk of...

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Main Authors: Rebecca Arden Harris, Sameed Ahmed M. Khatana, Judith A. Long
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Preventive Medicine Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211335525000361
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author Rebecca Arden Harris
Sameed Ahmed M. Khatana
Judith A. Long
author_facet Rebecca Arden Harris
Sameed Ahmed M. Khatana
Judith A. Long
author_sort Rebecca Arden Harris
collection DOAJ
description Objective: This study aimed to estimate and compare cardiometabolic disease (CMD) mortality in U.S. Black and White men during the transition from early adulthood to middle age. Methods: Using 2022 National Vital Statistics System data and standard period life table methods, we estimated the risk of CMD death in hypothetical cohorts of Black and White men from age 25 to 45 years. We estimated cumulative risk, excess mortality, years of lost life (YLL), and proportion of deaths due to CMD, stratifying by metabolic and cardiovascular disease. Results: Of the 325,134 Black men aged 25 years in the initial cohort, the cumulative risk of cardiometabolic death before age 45 was one in 63 individuals or 1.58 %. For White men, the risks were markedly lower. Of the 1,185,384 White men aged 25 years in the initial cohort, the cumulative risk of cardiometabolic death before age 45 was one in 158 individuals or 0.63 %. The study also found that of the 5141 expected CMD deaths in the Black cohort, 3090 or 60.10 % were excess deaths relative to the White cohort. Additionally, the proportion of all deaths due to CMD among Black men was 19.15 % rising from 6.02 % at age 25 to 38.00 % at age 45, compared with 11.10 % among White men, increasing from 4.57 % at age 25 to 19.79 % at age 45. The YLL for Black men averaged 6.72 months per person while White men averaged 2.94 months. Conclusions: This investigation shows profound racial disparities in CMD mortality from early to mid-adulthood.
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spelling doaj-art-3beb20f54ac54f16adc5f8b2125802242025-02-09T05:00:04ZengElsevierPreventive Medicine Reports2211-33552025-03-0151102997Cardiometabolic deaths in black and white men: Tracing the risks from early- to mid-adulthoodRebecca Arden Harris0Sameed Ahmed M. Khatana1Judith A. Long2Penn Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA, USA; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA; Department of Family Medicine and Community Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Corresponding author at: Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA; Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia, PA, USA; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USALeonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA; Division of General Internal Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USAObjective: This study aimed to estimate and compare cardiometabolic disease (CMD) mortality in U.S. Black and White men during the transition from early adulthood to middle age. Methods: Using 2022 National Vital Statistics System data and standard period life table methods, we estimated the risk of CMD death in hypothetical cohorts of Black and White men from age 25 to 45 years. We estimated cumulative risk, excess mortality, years of lost life (YLL), and proportion of deaths due to CMD, stratifying by metabolic and cardiovascular disease. Results: Of the 325,134 Black men aged 25 years in the initial cohort, the cumulative risk of cardiometabolic death before age 45 was one in 63 individuals or 1.58 %. For White men, the risks were markedly lower. Of the 1,185,384 White men aged 25 years in the initial cohort, the cumulative risk of cardiometabolic death before age 45 was one in 158 individuals or 0.63 %. The study also found that of the 5141 expected CMD deaths in the Black cohort, 3090 or 60.10 % were excess deaths relative to the White cohort. Additionally, the proportion of all deaths due to CMD among Black men was 19.15 % rising from 6.02 % at age 25 to 38.00 % at age 45, compared with 11.10 % among White men, increasing from 4.57 % at age 25 to 19.79 % at age 45. The YLL for Black men averaged 6.72 months per person while White men averaged 2.94 months. Conclusions: This investigation shows profound racial disparities in CMD mortality from early to mid-adulthood.http://www.sciencedirect.com/science/article/pii/S2211335525000361Cardiometabolic deathsExcess mortalityRacial disparitiesEarly adulthoodPeriod life tables
spellingShingle Rebecca Arden Harris
Sameed Ahmed M. Khatana
Judith A. Long
Cardiometabolic deaths in black and white men: Tracing the risks from early- to mid-adulthood
Preventive Medicine Reports
Cardiometabolic deaths
Excess mortality
Racial disparities
Early adulthood
Period life tables
title Cardiometabolic deaths in black and white men: Tracing the risks from early- to mid-adulthood
title_full Cardiometabolic deaths in black and white men: Tracing the risks from early- to mid-adulthood
title_fullStr Cardiometabolic deaths in black and white men: Tracing the risks from early- to mid-adulthood
title_full_unstemmed Cardiometabolic deaths in black and white men: Tracing the risks from early- to mid-adulthood
title_short Cardiometabolic deaths in black and white men: Tracing the risks from early- to mid-adulthood
title_sort cardiometabolic deaths in black and white men tracing the risks from early to mid adulthood
topic Cardiometabolic deaths
Excess mortality
Racial disparities
Early adulthood
Period life tables
url http://www.sciencedirect.com/science/article/pii/S2211335525000361
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