Immunohistochemical analysis of IDH1, ATRX, p53, and Ki-67 in glioblastoma and diffuse infiltrative glioma: Therapeutic and prognostic correlation

Immunohistochemical analysis of IDH1, ATRX, p53, and Ki-67 in glioblastoma and diffuse infiltrative glioma: Therapeutic and prognostic correlation

Background/Aim. The most common molecular alterations in high-grade astrocytoma include mutation of the isocitrate dehydrogenase (IDH) gene, loss of 1p19q, and p53 mutation. The aim of the study was to determine the prevalence of high-grade astrocytoma and glioblastoma and to examine the immunohisto...

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Bibliographic Details
Main Authors: Hasbay Bermal, Kayaselçuk Fazilet, Süner Halil İbrahim, Tufan Kadir
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2025-01-01
Series:Vojnosanitetski Pregled
Subjects:
astrocytoma
glioblastoma
ımmunohistochemistry
mutation
neoplasm grading
survival
Online Access:https://doiserbia.nb.rs/img/doi/0042-8450/2025/0042-84502500042H.pdf
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