Extracellular matrix deposition precedes muscle-tendon integration during murine forelimb morphogenesis

Extracellular matrix deposition precedes muscle-tendon integration during murine forelimb morphogenesis

Abstract The development of a functional musculoskeletal system requires the combination of contractile muscle and extracellular matrix (ECM)-rich tendons that transmit muscle-generated force to bone. Despite the different embryologic origins, muscle and tendon integrate at the myotendinous junction...

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Bibliographic Details
Main Authors: Yue Leng, Sarah N. Lipp, Ye Bu, Hannah Larson, Kathryn R. Jacobson, Haley A. Colling, Sarah Calve
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08653-0
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