Safety and immunogenicity of three dose levels of an investigational, highly purified Vero cell rabies vaccine: A randomized, controlled, observer-blinded, Phase II study with a simulated post-exposure regimen in healthy adults

Safety and immunogenicity of three dose levels of an investigational, highly purified Vero cell rabies vaccine: A randomized, controlled, observer-blinded, Phase II study with a simulated post-exposure regimen in healthy adults

A serum-free, highly purified rabies vaccine produced in Vero cells is under development. The initial formulation, PVRV-NG, was evaluated in five Phase II studies and subsequently reformulated (PVRV-NG2). This multicenter, observer-blinded Phase II study investigated the safety and immune response o...

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Bibliographic Details
Main Authors: Sylvie Pichon, Francoise Guinet-Morlot, Jamshid Saleh, Brandon Essink, Andrea-Clemencia Pineda-Peña, Annick Moureau, Celine Petit, Ada-Maria Minutello
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Immunogenicity
HDCV
post-exposure prophylaxis
rabies
safety
Vero cell rabies vaccine – serum free
Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2023.2275453
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