Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report
Small cell carcinoma (SmCC) generally occurs in the lung and extrapulmonary SmCC is a relatively rare entity. Here, we present a case of a 42-year-old male with SmCC of the larynx diagnosed as cT3N0M0. Concurrent chemoradiotherapy using cisplatin (CDDP) and etoposide (VP-16) was given, which achie...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Otolaryngology |
| Online Access: | http://dx.doi.org/10.1155/2012/316165 |
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| _version_ | 1832558789257068544 |
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| author | Susumu Nakahara Norihiko Takemoto Hidenori Inohara |
| author_facet | Susumu Nakahara Norihiko Takemoto Hidenori Inohara |
| author_sort | Susumu Nakahara |
| collection | DOAJ |
| description | Small cell carcinoma (SmCC) generally occurs in the lung and extrapulmonary SmCC is a relatively rare entity. Here, we present a case of a 42-year-old male with SmCC of the larynx diagnosed as cT3N0M0. Concurrent chemoradiotherapy using cisplatin (CDDP) and etoposide (VP-16) was given, which achieved complete response (CR). Lung metastasis became evident in 16 months whereas the locoregional control remained good. In spite of intensive chemotherapy using CDDP and irinotecan (CPT-11), the patient died of disease in 34 months after the first interview. Since the prognosis of laryngeal SmCC is extremely poor, organ preservation therapy should be considered instead of radical laryngectomy. |
| format | Article |
| id | doaj-art-3bd76a18718d4c5c89991b7a2b70face |
| institution | Kabale University |
| issn | 2090-6765 2090-6773 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Otolaryngology |
| spelling | doaj-art-3bd76a18718d4c5c89991b7a2b70face2025-02-03T01:31:34ZengWileyCase Reports in Otolaryngology2090-67652090-67732012-01-01201210.1155/2012/316165316165Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case ReportSusumu Nakahara0Norihiko Takemoto1Hidenori Inohara2Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanDepartment of Otolaryngology, Suita Municipal Hospital, 2-13-20 Katayama, Suita, Osaka 564-0082, JapanDepartment of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanSmall cell carcinoma (SmCC) generally occurs in the lung and extrapulmonary SmCC is a relatively rare entity. Here, we present a case of a 42-year-old male with SmCC of the larynx diagnosed as cT3N0M0. Concurrent chemoradiotherapy using cisplatin (CDDP) and etoposide (VP-16) was given, which achieved complete response (CR). Lung metastasis became evident in 16 months whereas the locoregional control remained good. In spite of intensive chemotherapy using CDDP and irinotecan (CPT-11), the patient died of disease in 34 months after the first interview. Since the prognosis of laryngeal SmCC is extremely poor, organ preservation therapy should be considered instead of radical laryngectomy.http://dx.doi.org/10.1155/2012/316165 |
| spellingShingle | Susumu Nakahara Norihiko Takemoto Hidenori Inohara Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report Case Reports in Otolaryngology |
| title | Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report |
| title_full | Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report |
| title_fullStr | Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report |
| title_full_unstemmed | Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report |
| title_short | Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report |
| title_sort | small cell carcinoma of the larynx treated by concurrent chemoradiotherapy a case report |
| url | http://dx.doi.org/10.1155/2012/316165 |
| work_keys_str_mv | AT susumunakahara smallcellcarcinomaofthelarynxtreatedbyconcurrentchemoradiotherapyacasereport AT norihikotakemoto smallcellcarcinomaofthelarynxtreatedbyconcurrentchemoradiotherapyacasereport AT hidenoriinohara smallcellcarcinomaofthelarynxtreatedbyconcurrentchemoradiotherapyacasereport |