Dynamical Analysis of HIV/AIDS Epidemic Model with Treatment

In this article, an epidemic model of HIV/AIDS with treatment is observed. This model consists of five populations: susceptible, educated susceptible, exposed, HIV infected, and AIDS infected. Antiretroviral therapy (ART) is one type of treatment that can be given to individual that is infected by H...

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Main Authors: Badria Ulfa, Trisilowati Trisilowati, Wuryansari M. K.
Format: Article
Language:English
Published: University of Brawijaya 2018-02-01
Series:Journal of Experimental Life Science
Subjects:
Online Access:https://jels.ub.ac.id/index.php/jels/article/view/244
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author Badria Ulfa
Trisilowati Trisilowati
Wuryansari M. K.
author_facet Badria Ulfa
Trisilowati Trisilowati
Wuryansari M. K.
author_sort Badria Ulfa
collection DOAJ
description In this article, an epidemic model of HIV/AIDS with treatment is observed. This model consists of five populations: susceptible, educated susceptible, exposed, HIV infected, and AIDS infected. Antiretroviral therapy (ART) is one type of treatment that can be given to individual that is infected by HIV. This medication can prevent the growth of the virus. Exposed individuals are given short-term antiretroviral treatment called Post Exposure Prophylaxis (PPP), while for infected individuals are given treatment by combining two or three types of antiretroviral drugs. Dynamical analysis is performed by determining equilibrium points and local stability analysis. Based on the analysis results, two equilibrium points are obtained, namely disease-free equilibrium point and endemic equilibrium points. The stability analysis shows that the free equilibrium point is locally asymptotically stable if R0 < 1 and the endemic equilibrium point is locally asymptotically stable under certain conditions. Numerical simulations show that giving two medications together has a greater effect in reducing the spread of the disease.
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language English
publishDate 2018-02-01
publisher University of Brawijaya
record_format Article
series Journal of Experimental Life Science
spelling doaj-art-3bce6bd4f0904cbabd54f5446377fda32025-08-20T03:07:57ZengUniversity of BrawijayaJournal of Experimental Life Science2087-28522338-16552018-02-01812329https://doi.org/10.21776/ub.jels.2018.008.01.04Dynamical Analysis of HIV/AIDS Epidemic Model with TreatmentBadria Ulfa0Trisilowati Trisilowati1Wuryansari M. K.2Universitas BrawijayaUniversitas BrawijayaBrawijaya UniversityIn this article, an epidemic model of HIV/AIDS with treatment is observed. This model consists of five populations: susceptible, educated susceptible, exposed, HIV infected, and AIDS infected. Antiretroviral therapy (ART) is one type of treatment that can be given to individual that is infected by HIV. This medication can prevent the growth of the virus. Exposed individuals are given short-term antiretroviral treatment called Post Exposure Prophylaxis (PPP), while for infected individuals are given treatment by combining two or three types of antiretroviral drugs. Dynamical analysis is performed by determining equilibrium points and local stability analysis. Based on the analysis results, two equilibrium points are obtained, namely disease-free equilibrium point and endemic equilibrium points. The stability analysis shows that the free equilibrium point is locally asymptotically stable if R0 < 1 and the endemic equilibrium point is locally asymptotically stable under certain conditions. Numerical simulations show that giving two medications together has a greater effect in reducing the spread of the disease.https://jels.ub.ac.id/index.php/jels/article/view/244antiretroviraldynamical analysishiv/aids.
spellingShingle Badria Ulfa
Trisilowati Trisilowati
Wuryansari M. K.
Dynamical Analysis of HIV/AIDS Epidemic Model with Treatment
Journal of Experimental Life Science
antiretroviral
dynamical analysis
hiv/aids.
title Dynamical Analysis of HIV/AIDS Epidemic Model with Treatment
title_full Dynamical Analysis of HIV/AIDS Epidemic Model with Treatment
title_fullStr Dynamical Analysis of HIV/AIDS Epidemic Model with Treatment
title_full_unstemmed Dynamical Analysis of HIV/AIDS Epidemic Model with Treatment
title_short Dynamical Analysis of HIV/AIDS Epidemic Model with Treatment
title_sort dynamical analysis of hiv aids epidemic model with treatment
topic antiretroviral
dynamical analysis
hiv/aids.
url https://jels.ub.ac.id/index.php/jels/article/view/244
work_keys_str_mv AT badriaulfa dynamicalanalysisofhivaidsepidemicmodelwithtreatment
AT trisilowatitrisilowati dynamicalanalysisofhivaidsepidemicmodelwithtreatment
AT wuryansarimk dynamicalanalysisofhivaidsepidemicmodelwithtreatment