Docosahexaenoic Acid Supplementation in Postnatal Growth Restricted Rats Does Not Normalize Lung Function or PPARγ Activity

Docosahexaenoic Acid Supplementation in Postnatal Growth Restricted Rats Does Not Normalize Lung Function or PPARγ Activity

The development of BPD in preterm neonates is increased by poor growth and nutritional deficits. The involvement of the fatty acid DHA in the development of BPD has been a focus for over a decade. However, recent clinical trials show that isolated DHA supplementation may increase BPD in subgroups of...

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Main Authors: Adrienne J. Cohen, Wesley R. Chidester, Daniel T. Wray, Nicolette Jessen, Aimee Jones, Cheylah Bitsui, James Zhao, J. Alan Maschek, James E. Cox, Camilia R. Martin, Lisa A. Joss-Moore
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomolecules
Subjects:
lung development
growth restriction
bronchopulmonary dysplasia
DHA
PPARγ
alternative splicing
Online Access:https://www.mdpi.com/2218-273X/15/4/551
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