Microbial Biofilms: Modern Concepts
The review discusses modern ideas concerning the biofilms of microorganisms. The development phases, structure and components of biofilms are considered as possible antibiotic resistance factors (ARF). Examples of various types of ADB in biofilm bacteria are given. The process of collective regulati...
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| Format: | Article |
| Language: | Russian |
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LLC "Publishing House OKI"
2020-08-01
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| Series: | Антибиотики и Химиотерапия |
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| Online Access: | https://www.antibiotics-chemotherapy.ru/jour/article/view/740 |
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| _version_ | 1849693092974690304 |
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| author | A. A. Khryanin |
| author_facet | A. A. Khryanin |
| author_sort | A. A. Khryanin |
| collection | DOAJ |
| description | The review discusses modern ideas concerning the biofilms of microorganisms. The development phases, structure and components of biofilms are considered as possible antibiotic resistance factors (ARF). Examples of various types of ADB in biofilm bacteria are given. The process of collective regulation through coordination of gene expression in a bacterial population that mediates the specific behavior of cells is considered. Various approaches that affect the components of biofilms have been evaluated in order to reduce their resistance/integrity using a combination of antibacterial drugs and enzymes of various origins. Promising methods for influencing matrix components, signaling molecules, and adhesion factors are recognized. A promising way to increase the effectiveness of the effect of antibiotics on biofilms is the use of hydrolytic enzymes. |
| format | Article |
| id | doaj-art-3bc59b3040ab4545a04a2198190bb01f |
| institution | DOAJ |
| issn | 0235-2990 |
| language | Russian |
| publishDate | 2020-08-01 |
| publisher | LLC "Publishing House OKI" |
| record_format | Article |
| series | Антибиотики и Химиотерапия |
| spelling | doaj-art-3bc59b3040ab4545a04a2198190bb01f2025-08-20T03:20:32ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-08-01655-6707710.37489/0235-2990-2020-65-5-6-70-77730Microbial Biofilms: Modern ConceptsA. A. Khryanin0Novosibirsk State Medical UniversityThe review discusses modern ideas concerning the biofilms of microorganisms. The development phases, structure and components of biofilms are considered as possible antibiotic resistance factors (ARF). Examples of various types of ADB in biofilm bacteria are given. The process of collective regulation through coordination of gene expression in a bacterial population that mediates the specific behavior of cells is considered. Various approaches that affect the components of biofilms have been evaluated in order to reduce their resistance/integrity using a combination of antibacterial drugs and enzymes of various origins. Promising methods for influencing matrix components, signaling molecules, and adhesion factors are recognized. A promising way to increase the effectiveness of the effect of antibiotics on biofilms is the use of hydrolytic enzymes.https://www.antibiotics-chemotherapy.ru/jour/article/view/740biofilmsmatrixpersistersantibiotic resistancequorum sensingenzymes |
| spellingShingle | A. A. Khryanin Microbial Biofilms: Modern Concepts Антибиотики и Химиотерапия biofilms matrix persisters antibiotic resistance quorum sensing enzymes |
| title | Microbial Biofilms: Modern Concepts |
| title_full | Microbial Biofilms: Modern Concepts |
| title_fullStr | Microbial Biofilms: Modern Concepts |
| title_full_unstemmed | Microbial Biofilms: Modern Concepts |
| title_short | Microbial Biofilms: Modern Concepts |
| title_sort | microbial biofilms modern concepts |
| topic | biofilms matrix persisters antibiotic resistance quorum sensing enzymes |
| url | https://www.antibiotics-chemotherapy.ru/jour/article/view/740 |
| work_keys_str_mv | AT aakhryanin microbialbiofilmsmodernconcepts |