Innovative Approaches in Acyl Sonogashira Coupling: Impact of Supported CuNPs and Cu-PdNPs Nanocatalysts
In this work, we present our findings on the acyl Sonogashira coupling catalyzed by copper nanoparticles (CuNPs) or bimetallic copper–palladium (4:1 molar ratio) nanoparticles (Cu-PdNPs) immobilized in various inorganic materials. Both catalysts allowed the synthesis of ynones in good to excellent y...
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2023-11-01
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| author | Santiago Stabile Gabriel Radivoy |
| author_facet | Santiago Stabile Gabriel Radivoy |
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| description | In this work, we present our findings on the acyl Sonogashira coupling catalyzed by copper nanoparticles (CuNPs) or bimetallic copper–palladium (4:1 molar ratio) nanoparticles (Cu-PdNPs) immobilized in various inorganic materials. Both catalysts allowed the synthesis of ynones in good to excellent yields. Cu-PdNPs supported on Celite exhibit high activity, allowing reactions to proceed at room temperature, whereas the monometallic CuNPs catalysts required reactions to be carried out at 80 °C. In addition, Cu-PdNPs/Celite can be also used in Sonogashira coupling reactions with iodoarenes. Both types of catalysts can be reused without any pre-treatment after separation from the reaction medium and subsequent washing. |
| format | Article |
| id | doaj-art-3bc3a0b98acc45ea85a072fcb195738a |
| institution | DOAJ |
| issn | 2673-4583 |
| language | English |
| publishDate | 2023-11-01 |
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| spelling | doaj-art-3bc3a0b98acc45ea85a072fcb195738a2025-08-20T02:53:40ZengMDPI AGChemistry Proceedings2673-45832023-11-011417610.3390/ecsoc-27-16090Innovative Approaches in Acyl Sonogashira Coupling: Impact of Supported CuNPs and Cu-PdNPs NanocatalystsSantiago Stabile0Gabriel Radivoy1Instituto de Química del Sur, INQUISUR (CONICET-UNS), NANOSYN, Departamento de Química, Universidad Nacional del Sur, Avda. Alem 1253, Bahía Blanca 8000, ArgentinaInstituto de Química del Sur, INQUISUR (CONICET-UNS), NANOSYN, Departamento de Química, Universidad Nacional del Sur, Avda. Alem 1253, Bahía Blanca 8000, ArgentinaIn this work, we present our findings on the acyl Sonogashira coupling catalyzed by copper nanoparticles (CuNPs) or bimetallic copper–palladium (4:1 molar ratio) nanoparticles (Cu-PdNPs) immobilized in various inorganic materials. Both catalysts allowed the synthesis of ynones in good to excellent yields. Cu-PdNPs supported on Celite exhibit high activity, allowing reactions to proceed at room temperature, whereas the monometallic CuNPs catalysts required reactions to be carried out at 80 °C. In addition, Cu-PdNPs/Celite can be also used in Sonogashira coupling reactions with iodoarenes. Both types of catalysts can be reused without any pre-treatment after separation from the reaction medium and subsequent washing.https://www.mdpi.com/2673-4583/14/1/76acyl Sonogashira couplingnanocatalystnanoparticlescopperpalladium |
| spellingShingle | Santiago Stabile Gabriel Radivoy Innovative Approaches in Acyl Sonogashira Coupling: Impact of Supported CuNPs and Cu-PdNPs Nanocatalysts Chemistry Proceedings acyl Sonogashira coupling nanocatalyst nanoparticles copper palladium |
| title | Innovative Approaches in Acyl Sonogashira Coupling: Impact of Supported CuNPs and Cu-PdNPs Nanocatalysts |
| title_full | Innovative Approaches in Acyl Sonogashira Coupling: Impact of Supported CuNPs and Cu-PdNPs Nanocatalysts |
| title_fullStr | Innovative Approaches in Acyl Sonogashira Coupling: Impact of Supported CuNPs and Cu-PdNPs Nanocatalysts |
| title_full_unstemmed | Innovative Approaches in Acyl Sonogashira Coupling: Impact of Supported CuNPs and Cu-PdNPs Nanocatalysts |
| title_short | Innovative Approaches in Acyl Sonogashira Coupling: Impact of Supported CuNPs and Cu-PdNPs Nanocatalysts |
| title_sort | innovative approaches in acyl sonogashira coupling impact of supported cunps and cu pdnps nanocatalysts |
| topic | acyl Sonogashira coupling nanocatalyst nanoparticles copper palladium |
| url | https://www.mdpi.com/2673-4583/14/1/76 |
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